OMIA:000155 : C3 deficiency

Categories: Immune system phene

Possible human homologues (MIM numbers): 613779 (trait) , 120700 (gene)

Links to relevant human diseases in MONDO:

Cross-species summary: Complement component 3 consists of two chains, alpha and beta, linked covalently by disulphide bonds. In humans and mice (and therefore presumably in all mammals), the two chains are encoded by a single gene (the C3 gene).

Species in which this phene is found:
dog (Canis lupus familiaris)
rabbit (Oryctolagus cuniculus)
domestic guinea pig (Cavia porcellus)

Edit History


  • Created by Frank Nicholas on 03 May 2005
  • Changed by Frank Nicholas on 03 Sep 2012
  • Changed by Imke Tammen2 on 19 Mar 2022
  • Changed by Imke Tammen2 on 27 May 2023