OMIA:000684-9615 : Myasthenia in Canis lupus familiaris (dog) |
In other species: domestic cat , taurine cattle , Amur tiger
Categories: Nervous system phene
Possibly relevant human trait(s) and/or gene(s)s (MIM numbers): 254200 (trait) , 254210 (trait)
Links to MONDO diseases: No links.
Mendelian trait/disorder: yes
Considered a defect: yes
Key variant known: no
Cross-species summary: Myasthenia is a syndrome of impaired neuromuscular transmission. The syndrome can occur as an acquired autoimmune disorder (myasthenia gravis) or as a congenital genetic disorder (see also separate gene-specific myasthenic syndrome entries). Phene was renamed from 'Myasthenia gravis' to 'Myasthenia' [14/10/2022]
Genetic engineering:
Unknown
Have human generated variants been created, e.g. through genetic engineering and gene editing
Cite this entry
Nicholas, F. W., Tammen, I., & Sydney Informatics Hub. (2005). OMIA:000684-9615: Online Mendelian Inheritance in Animals (OMIA) [dataset]. https://omia.org/. https://doi.org/10.25910/2AMR-PV70
References
Note: the references are listed in reverse chronological order (from the most recent year to the earliest year), and alphabetically by first author within a year.
| 2020 | Mignan, T., Targett, M., Lowrie, M. : |
| Classification of myasthenia gravis and congenital myasthenic syndromes in dogs and cats. J Vet Intern Med 34:1707-1717, 2020. Pubmed reference: 32668077. DOI: 10.1111/jvim.15855. | |
| 2016 | Shelton, G.D. : |
| Myasthenia gravis and congenital myasthenic syndromes in dogs and cats: A history and mini-review. Neuromuscul Disord 26:331-4, 2016. Pubmed reference: 27080328. DOI: 10.1016/j.nmd.2016.03.002. | |
| 2011 | Khorzad, R., Whelan, M., Sisson, A., Shelton, GD. : |
| Myasthenia gravis in dogs with an emphasis on treatment and critical care management. J Vet Emerg Crit Care (San Antonio) 21:193-208, 2011. Pubmed reference: 21631705. DOI: 10.1111/j.1476-4431.2011.00636.x. | |
| 2005 | Dickinson, PJ., Sturges, BK., Shelton, GD., LeCouteur, RA. : |
| Congenital myasthenia gravis in Smooth-Haired Miniature Dachshund dogs. J Vet Intern Med 19:920-3, 2005. Pubmed reference: 16355692. | |
| 2002 | Shelton, G.D. : |
| Myasthenia gravis and disorders of neuromuscular transmission Veterinary Clinics of North America - Small Animal Practice 32:189-+, 2002. | |
| 2001 | Shelton, G.D., Skeie, G.O., Kass, P.H., Aarli, J.A. : |
| Titin and ryanodine receptor autoantibodies in dogs with thymoma and late-onset myasthenia gravis Veterinary Immunology & Immunopathology 78:97-105, 2001. | |
| 2000 | Ridyard, A.E., Rhind, S.M., French, A.T., Munro, E.A.C., Hill, P.B. : |
| Myasthenia gravis associated with cutaneous lymphoma in a dog Journal of Small Animal Practice 41:348-351, 2000. Pubmed reference: 11002936. | |
| 1999 | Dewey, C.W., Coates, J.R., Ducote, J.M., Meeks, J.C., Fradkin, J.M. : |
| Azathioprine therapy for acquired myasthenia gravis in five dogs Journal of the American Animal Hospital Association 35:396-402, 1999. Pubmed reference: 10493415. | |
| Lipsitz, D., Berry, J.L., Shelton, G.D. : | |
| Inherited predisposition to myasthenia gravis in Newfoundlands Journal of the American Veterinary Medical Association 215:956-+, 1999. Pubmed reference: 10511859. | |
| Shelton, G.D. : | |
| Acquired myasthenia gravis: what we have learned from experimental and spontaneous animal models Veterinary Immunology & Immunopathology 69:239-249, 1999. | |
| Yoshioka, T., Uzuka, Y., Tanabe, S., Saraskina, T., Ishiguro, N. : | |
| Molecular cloning of the canine nicotinic acetylcholine receptor alpha-subunit gene and development of the ELISA method to diagnose myasthenia gravis Veterinary Immunology & Immunopathology 72:315-324, 1999. | |
| 1998 | King, L.G., Vite, C.H. : |
| Acute fulminating myasthenia gravis in five dogs Journal of the American Veterinary Medical Association 212:830 ff., 1998. | |
| Shelton, G.D. : | |
| Myasthenia gravis - lessons from the past 10 years Journal of Small Animal Practice 39:368-372, 1998. Pubmed reference: 9741871. | |
| 1997 | Dewey, C.W. : |
| Acquired myasthenia gravis in dogs .1 Compendium on Continuing Education for the Practicing Veterinarian 19:1340 ff., 1997. | |
| Dewey, C.W., Bailey, C.S., Shelton, G.D., Kass, P.H., Cardinet, G.H. : | |
| Clinical forms of acquired myasthenia gravis in dogs - 25 cases (1988-1995) Journal of Veterinary Internal Medicine 11:50-57, 1997. Pubmed reference: 9127290. | |
| Shelton, G.D., Schule, A., Kass, P.H. : | |
| Risk factors for acquired myasthenia gravis in dogs - 1,154 cases (1991-1995) Journal of the American Veterinary Medical Association 211:1428 ff., 1997. | |
| Webb, A.A., Taylor, S.M., Mcphee, L. : | |
| Focal myasthenia gravis in a dog Canadian Veterinary Journal - Revue Veterinaire Canadienne 38:493-495, 1997. | |
| 1996 | Lainesse, M.F.C., Taylor, S.M., Myers, S.L., Haines, D., Fowler, J.D. : |
| Focal myasthenia gravis as a paraneoplastic syndrome of canine thymoma - improvement following thymectomy Journal of the American Animal Hospital Association 32:111-117, 1996. Pubmed reference: 8680916. | |
| 1995 | Dewey, C.W., Shelton, G.D., Bailey, C.S., Willard, M.D., Podell, M., Collins, R.L. : |
| Neuromuscular dysfunction in five dogs with acquired myasthenia gravis and presumptive hypothyroidism Progress in Veterinary Neurology 6:117-123, 1995. | |
| Hackett, T.B., Vanpelt, D.R., Willard, M.D., Martin, L.G., Shelton, G.D., Wingfield, W.E. : | |
| Third degree atrioventricular block and acquired myasthenia gravis in four dogs Journal of the American Veterinary Medical Association 206:1173-1176, 1995. Pubmed reference: 7768738. | |
| 1994 | Kohn, B., Waxenberger, M. : |
| Myasthenia Gravis in the Dog Praktische Tierarzt 75:118-120, 1994. | |
| Vanham, L.M.L. : | |
| A Myasthenic-Like Syndrome in Young Related Mongrel Dogs Vlaams Diergeneeskundig Tijdschrift 63:146-149, 1994. | |
| 1992 | Hopkins, A.L. : |
| Canine Myasthenia Gravis Journal of Small Animal Practice 33:477-484, 1992. | |
| 1990 | Beddow, B. : |
| Myasthenia Gravis in a Dog Veterinary Record 127:244, 1990. Pubmed reference: 2260272. | |
| Moore, A.S., Madewell, B.R., Cardinet, G.H., Shelton, G.D. : | |
| Osteogenic Sarcoma and Myasthenia Gravis in a Dog Journal of the American Veterinary Medical Association 197:226-227, 1990. Pubmed reference: 2384323. | |
| Shelton, G.D., Fujii, Y., Lindstrom, J. : | |
| Mitogen Stimulation of Canine Normal and Myasthenia Gravis Lymphocytes Veterinary Immunology and Immunopathology 24:1-9, 1990. Pubmed reference: 2316185. | |
| 1976 | Jenkins, W.L., Dyk, E. van, McDonald, C.B. : |
| Myasthenia gravis in a Fox Terrier litter Journal of the South African Veterinary Association 47:59-62, 1976. Pubmed reference: 1263198. | |
| 1974 | Palmer, A.C., Barker, J. : |
| Myasthenia in the dog. Vet Rec 95:452-4, 1974. Pubmed reference: 4446286. |
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- Created by Frank Nicholas on 06 Sep 2005