OMIA:000832-9913 : Progressive spinal myelopathy in Bos taurus (taurine cattle)

Categories: Nervous system phene

Links to MONDO diseases: No links.

Mendelian trait/disorder: unknown

Considered a defect: yes

History: Richards and Edwards (1986): "Ataxia of the hind limbs in nine calves was associated with degenerative lesions in spinal white matter and neuronal chromatolysis in red nucleus, spinal grey matter and various nuclei of the medulla oblongata and cerebellum. The clinical signs and lesions ... occurred predominantly in calves of the Murray Grey breed." Edwards et al. (1988): "From analysis of pedigrees and the results of the breeding experiment it was concluded that the condition was inherited as an autosomal recessive condition in Murray Grey cattle."

Genetic engineering: Unknown
Have human generated variants been created, e.g. through genetic engineering and gene editing

Breed: Murray Grey (Cattle) (VBO_0000312).
Breeds in which the phene has been documented. For breeds in which a likely causal variant has been documented, see the variant table below

Cite this entry

Nicholas, F. W., Tammen, I., & Sydney Informatics Hub. (2020). OMIA:000832-9913: Online Mendelian Inheritance in Animals (OMIA) [dataset]. https://omia.org/. https://doi.org/10.25910/2AMR-PV70

References

Note: the references are listed in reverse chronological order (from the most recent year to the earliest year), and alphabetically by first author within a year.

1988 Edwards, J.R., Richards, R.B., Carrick, M.J. :
Inherited progressive spinal myelopathy in Murray Grey cattle Australian Veterinary Journal 65:108-109, 1988. Pubmed reference: 3390088.
1986 Richards, R.B., Edwards, J.R. :
A progressive spinal myelinopathy in beef cattle. Vet Pathol 23:35-41, 1986. Pubmed reference: 3946053. DOI: 10.1177/030098588602300106.

Edit History


  • Created by Frank Nicholas on 06 Sep 2005
  • Changed by Imke Tammen2 on 04 Dec 2020