OMIA:001041-9615 : Ventricular septal defect in Canis lupus familiaris (dog) |
In other species: chicken , turkey , domestic cat , horse , pig , taurine cattle , goat , sheep , rabbit , alpaca
Categories: Cardiovascular system phene
Possibly relevant human trait(s) and/or gene(s)s (MIM numbers): 614429 (trait) , 614431 (trait) , 614432 (trait)
Links to MONDO diseases: No links.
Mendelian trait/disorder: no
Mode of inheritance: Multifactorial
Considered a defect: yes
Key variant known: no
Cross-species summary: A congenital heart defect characterised by persistent patency (open-ness) of the ventricular septum, permitting flow of blood directly between ventricles, bypassing the pulmonary circulation and resulting in various degrees of cyanosis (blue discolouration of the skin) due to oxygen deficiency. Clinical signs include systolic murmur and a palpable thrill on both sides of the chest, dyspnoea and poor tolerance of exercise.
Genetic engineering:
Unknown
Have human generated variants been created, e.g. through genetic engineering and gene editing
Cite this entry
Nicholas, F. W., Tammen, I., & Sydney Informatics Hub. (2015). OMIA:001041-9615: Online Mendelian Inheritance in Animals (OMIA) [dataset]. https://omia.org/. https://doi.org/10.25910/2AMR-PV70
References
Note: the references are listed in reverse chronological order (from the most recent year to the earliest year), and alphabetically by first author within a year.
| 2023 | Aherne, M. : |
| Cardiac disease and screening in breeding dogs. Vet Clin North Am Small Anim Pract , 2023. Pubmed reference: 37353418. DOI: 10.1016/j.cvsm.2023.05.001. | |
| Schrope, D. : | |
| Acquired infundibular pulmonary stenosis associated with a congenital membranous ventricular septal defect (Gasul phenomenon) in a dog and discussion regarding causes of infundibular stenosis. J Vet Cardiol 47:64-69, 2023. Pubmed reference: 37247530. DOI: 10.1016/j.jvc.2023.05.001. | |
| 2020 | Brambilla, P.G., Polli, M., Pradelli, D., Papa, M., Rizzi, R., Bagardi, M., Bussadori, C. : |
| Epidemiological study of congenital heart diseases in dogs: Prevalence, popularity, and volatility throughout twenty years of clinical practice. PLoS One 15:e0230160, 2020. Pubmed reference: 32716943. DOI: 10.1371/journal.pone.0230160. | |
| 2017 | Belanger, J.M., Bellumori, T.P., Bannasch, D.L., Famula, T.R., Oberbauer, A.M. : |
| Correlation of neuter status and expression of heritable disorders. Canine Genet Epidemiol 4:6, 2017. Pubmed reference: 28560045. DOI: 10.1186/s40575-017-0044-6. | |
| 2015 | Schrope, D.P. : |
| Prevalence of congenital heart disease in 76,301 mixed-breed dogs and 57,025 mixed-breed cats. J Vet Cardiol 17:192-202, 2015. Pubmed reference: 26363941. DOI: 10.1016/j.jvc.2015.06.001. | |
| 2013 | Bellumori, T.P., Famula, T.R., Bannasch, D.L., Belanger, J.M., Oberbauer, A.M. : |
| Prevalence of inherited disorders among mixed-breed and purebred dogs: 27,254 cases (1995-2010). J Am Vet Med Assoc 242:1549-55, 2013. Pubmed reference: 23683021. DOI: 10.2460/javma.242.11.1549. | |
| 2011 | Oliveira, P., Domenech, O., Silva, J., Vannini, S., Bussadori, R., Bussadori, C. : |
| Retrospective review of congenital heart disease in 976 dogs. J Vet Intern Med 25:477-83, 2011. Pubmed reference: 21418326. DOI: 10.1111/j.1939-1676.2011.0711.x. | |
| 2009 | Diez-Prieto, I., García-Rodríguez, B., Ríos-Granja, A., Cano-Rábano, M., Peña-Penabad, M., García, C.P. : |
| Cardiac conotruncal malformations in a family of Beagle dogs. J Small Anim Pract 50:597-603, 2009. Pubmed reference: 19814768. DOI: 10.1111/j.1748-5827.2009.00815.x. | |
| 2005 | Shimizu, M., Tanaka, R., Hirao, H., Kobayashi, M., Shimamura, S., Maruo, K., Yamane, Y. : |
| Percutaneous transcatheter coil embolization of a ventricular septal defect in a dog. J Am Vet Med Assoc 226:69-72, 52-3, 2005. Pubmed reference: 15646575. | |
| 2003 | Baumgartner, C., Glaus, TM. : |
| [Congenital cardiac diseases in dogs: a retrospective analysis]. Schweiz Arch Tierheilkd 145:527-33, 535-6, 2003. Pubmed reference: 14639823. | |
| Rausch, W.P., Keene, B.W. : | |
| Spontaneous resolution of an isolated ventricular septal defect in a dog Journal of the American Veterinary Medical Association 223:219-20, 197, 2003. Pubmed reference: 12875450. | |
| 1999 | Gehlen, H., Stadler, P., Deegen, E. : |
| Colour doppler technique and heart catheterization for haemodynamic evaluation of a ventricular septal defect - Case report Pferdeheilkunde 15:313-+, 1999. | |
| Gehlen, H., Stadler, P., Deegen, E. : | |
| Colour doppler technique and heart catheterization for haemodynamic evaluation of a ventricular septal defect - Case report Pferdeheilkunde 15:233-+, 1999. | |
| 1998 | Vollmar, A., Huttig, A. : |
| Ventricular septal defect associated with aortic regurgitation in six dogs [German] Kleintierpraxis 43:911-+, 1998. | |
| 1995 | Hunt, G.B., Pearson, M.R.B., Bellenger, C.R., Malik, R. : |
| Ventricular septal defect repair in a small dog using cross-circulation Australian Veterinary Journal 72:379-382, 1995. Pubmed reference: 8599570. | |
| Skarda, R.T., Bednarski, R.M., Muir, W.W., Hubbell, J.A.E., Mason, D.E. : | |
| Sedation and anesthesia in dogs and cats with cardiovascular disease Schweizer Archiv Fur Tierheilkunde 137:312-321, 1995. Pubmed reference: 7569846. | |
| 1993 | Hagen, A., Keene, B. : |
| Presentation of a Ventricular Septum Defect in a Dog by Color- Doppler-Echocardiography, by Angiography and by Selective Oxymetry Schweizer Archiv Fur Tierheilkunde 135:268-271, 1993. Pubmed reference: 8211054. | |
| 1985 | Matsuoka, S., Miyauchi, Y., Nakatsu, T., Yuasa, Y., Ueda, H., Miyao, M. : |
| Effect of respiratory acidosis on ventricular shunt flow and hemodynamics in dogs with ventricular septal defect. Jpn Circ J 49:499-506, 1985. Pubmed reference: 3927033. | |
| 1977 | Eyster, G.E., Whipple, R.D., Anderson, L.K., Evans, A.T., O'Handley, P. : |
| Pulmonary artery banding for ventricular septal defect in dogs and cats. J Am Vet Med Assoc 170:434-8, 1977. Pubmed reference: 557030. | |
| 1974 | Patterson, D.F., Pyle, R.L., Mierop, L. van, Melbin, J., Olson, M. : |
| Hereditary defects of the conotruncal septum in Keeshond dogs: pathologic and genetic studies American Journal of Cardiology 34:187-205, 1974. Pubmed reference: 4843154. | |
| 1973 | Mulvihill, J.J., Priester, W.A. : |
| Congenital heart disease in dogs: epidemiologic similarities to man. Teratology 7:73-7, 1973. Pubmed reference: 4693746. DOI: 10.1002/tera.1420070111. | |
| 1972 | [No authors listed] : |
| Correction of a ventricular septal defect in a dog. J Am Vet Med Assoc 161:507-12, 1972. Pubmed reference: 5052217. |
Edit History
- Created by Frank Nicholas on 06 Sep 2005
- Changed by Frank Nicholas on 12 Dec 2015