OMIA:001071-9823 : Wilson disease in Sus scrofa (pig) |
In other species: dog , domestic cat , taurine cattle , sheep
Categories: Liver/biliary system phene
Possibly relevant human trait(s) and/or gene(s)s (MIM numbers): 277900 (trait) , 606882 (gene)
Links to MONDO diseases:
Mendelian trait/disorder: unknown
Considered a defect: yes
Cross-species summary: A disorder of copper metabolism, due to a deficiency of ceruloplasmin, which forms a complex with copper. The excess copper is deposited in the brain (causing mental retardation) or the liver (causing jaundice and cirrhosis).
Genetic engineering:
Unknown
Have human generated variants been created, e.g. through genetic engineering and gene editing
Cite this entry
Nicholas, F. W., Tammen, I., & Sydney Informatics Hub. (2005). OMIA:001071-9823: Online Mendelian Inheritance in Animals (OMIA) [dataset]. https://omia.org/. https://doi.org/10.25910/2AMR-PV70
Reference
| 1987 | Howell, J.M., Wiener, G., Gawthorne, J.M. : |
| The genetics of copper metabolism in animals and man :45-61, 1987. |
Edit History
- Created by Frank Nicholas on 06 Sep 2005