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OMIA:000344-10047 : Epilepsy in Meriones unguiculatus (Mongolian gerbil)

In other species: chicken , white-tufted-ear marmoset , dog , domestic cat , horse , taurine cattle , rabbit , golden hamster , prairie vole

Categories: Behaviour / neurological phene

Possibly relevant human trait(s) and/or gene(s)s (MIM numbers): 104130 (trait) , 117100 (trait) , 121200 (trait) , 121201 (trait) , 125370 (trait) , 132090 (trait) , 132100 (trait) , 132300 (trait) , 159600 (trait) , 182610 (trait) , 203600 (trait) , 208700 (trait) , 220300 (trait) , 226750 (trait) , 226800 (trait) , 226810 (trait) , 226850 (trait) , 254770 (trait) , 254780 (trait) , 254800 (trait) , 266270 (trait) , 267740 (trait) , 270805 (trait) , 301900 (trait) , 310370 (trait) , 545000 (trait) , 600131 (trait) , 600143 (trait) , 600512 (trait) , 600513 (trait) , 600669 (trait) , 601068 (trait) , 245570 (trait)

Links to MONDO diseases: No links.

Mendelian trait/disorder: unknown

Considered a defect: yes

Genetic engineering: Unknown
Have human generated variants been created, e.g. through genetic engineering and gene editing

Cite this entry

Nicholas, F. W., Tammen, I., & Sydney Informatics Hub. (2011). OMIA:000344-10047: Online Mendelian Inheritance in Animals (OMIA) [dataset]. https://omia.org/. https://doi.org/10.25910/2AMR-PV70

References

Note: the references are listed in reverse chronological order (from the most recent year to the earliest year), and alphabetically by first author within a year.

2008 Matsuda, Y., Saito, N., Yamamoto, K., Niitsu, T., Kogure, S. :
Effects of the Ih blockers CsCl and ZD7288 on inherited epilepsy in Mongolian gerbils. Exp Anim 57:377-84, 2008. Pubmed reference: 18633160.
2003 Fujisawa, N., Maeda, Y., Yamamoto, Y., Sato, N.L., Niimura, S. :
Newly established low seizure susceptible and seizure-prone inbred strains of Mongolian gerbil. Exp Anim 52:169-72, 2003. Pubmed reference: 12806893.
Kang, T.C., An, S.J., Park, S.K., Hwang, I.K., Seo, M.O., Kim, H.S., Kang, J.H., Kwon, O.S., Won, M.H. :
The somatostatin receptors in the normal and epileptic hippocampus of the gerbil: subtype-specific localization and its alteration. Brain Res 986:91-102, 2003. Pubmed reference: 12965233.
2002 Buckmaster, P.S., Wong, E.H. :
Evoked responses of the dentate gyrus during seizures in developing gerbils with inherited epilepsy. J Neurophysiol 88:783-93, 2002. Pubmed reference: 12163530.
1997 Scotti, A.L., Bollag, O., Kalt, G., Nitsch, C. :
Loss of perikaryal parvalbumin immunoreactivity from surviving GABAergic neurons in the CA1 field of epileptic gerbils. Hippocampus 7:524-35, 1997. Pubmed reference: 9347349. DOI: 10.1002/(SICI)1098-1063(1997)7:5<524::AID-HIPO8>3.0.CO;2-G.
1996 Buckmaster, P.S., Tam, E., Schwartzkroin, P.A. :
Electrophysiological correlates of seizure sensitivity in the dentate gyrus of epileptic juvenile and adult gerbils. J Neurophysiol 76:2169-80, 1996. Pubmed reference: 8899592.
1991 Jobe, P.C., Mishra, P.K., Ludvig, N., Dailey, J.W. :
Scope and contribution of genetic models to an understanding of the epilepsies. Crit Rev Neurobiol 6:183-220, 1991. Pubmed reference: 1773452.
1989 Fisher, R.S. :
Animal models of the epilepsies. Brain Res Brain Res Rev 14:245-78, 1989. Pubmed reference: 2679941.
1987 Bartoszyk, G.D., Hamer, M. :
The genetic animal model of reflex epilepsy in the Mongolian gerbil: differential efficacy of new anticonvulsive drugs and prototype antiepileptics. Pharmacol Res Commun 19:429-40, 1987. Pubmed reference: 3659116.
1986 Lee, R.J., McCabe, R.T., Wamsley, J.K., Olsen, R.W., Lomax, P. :
Opioid receptor alterations in a genetic model of generalized epilepsy. Brain Res 380:76-82, 1986. Pubmed reference: 3019467.
Olsen, R.W., Wamsley, J.K., Lee, R.J., Lomax, P. :
Benzodiazepine/barbiturate/GABA receptor-chloride ionophore complex in a genetic model for generalized epilepsy. Adv Neurol 44:365-78, 1986. Pubmed reference: 3010677.
1983 Lee, R.J., Bajorek, J.G., Lomax, P. :
Opioid peptides and seizures in the spontaneously epileptic Mongolian gerbil. Life Sci :567-70, 1983. Pubmed reference: 6141501.
1976 Cox, B., Lomax, P. :
Brain amines and spontaneous epileptic seizures in the Mongolian gerbil. Pharmacol Biochem Behav 4:263-7, 1976. Pubmed reference: 180544.
1975 Loskota, W.J., Lomax, P. :
The Mongolian gerbil (Meriones unguiculatus) as a model for the study of the epilepsies: EEG records of seizures. Electroencephalogr Clin Neurophysiol 38:597-604, 1975. Pubmed reference: 50185.
1974 Loskota, W.J., Lomax, P., Rich, S.T. :
The gerbil as a model for the study of the epilepsies. Seizure patterns and ontogenesis. Epilepsia 15:109-19, 1974. Pubmed reference: 4523020.
1968 Goldblatt, D. :
Seizure disorder in gerbils. Neurology 18:303-4, 1968. Pubmed reference: 5690409.

Edit History


  • Created by Frank Nicholas on 22 Sep 2008
  • Changed by Frank Nicholas on 27 Nov 2011