OMIA:000133-9940 : Blood group system M in Ovis aries (sheep)

In other species: pig , aoudad , taurine cattle , goat , mouflon

Categories: Haematopoietic system phene

Links to MONDO diseases: No links.

Mendelian trait/disorder: yes

Considered a defect: no

Key variant known: no

Cross-species summary: Each blood group system consists of a set of blood types, each of which corresponds to a particular antigen (usually a glycoprotein) on the surface of red blood cells. The different types within a system are the result of the action of different alleles at a locus that usually encodes an enzyme that catalyses the creation of the feature of the glycoprotein unique to that type, e.g. the presence of a particular sugar at the end of a short chain of sugars.

Species-specific description: This locus has at least 4 alleles. The Mb factor of this system (previously called the L factor) appears to be an inhibitor of potassium transport; in fact, this locus may be identical with the potassium transport locus.

Genetic engineering: Unknown
Have human generated variants been created, e.g. through genetic engineering and gene editing

Cite this entry

Nicholas, F. W., Tammen, I., & Sydney Informatics Hub. (2020). OMIA:000133-9940: Online Mendelian Inheritance in Animals (OMIA) [dataset]. https://omia.org/. https://doi.org/10.25910/2AMR-PV70

References

Note: the references are listed in reverse chronological order (from the most recent year to the earliest year), and alphabetically by first author within a year.

1992 Nguyen, T.C., Morera, L., Llanes, D., Leger, P. :
Sheep Blood Polymorphism and Genetic Divergence Between French Rambouillet and Spanish Merino - Role of Genetic Drift Animal Genetics 23:325-332, 1992. Pubmed reference: 1503271.
1983 Bell, K., Agar, N.S., Board, P.G. :
The blood groups of domestic mammals :133-164, 1983.
1982 Casati, M.Z., Caroll, A. :
[Immunogenetic characterisation of a population of Varese sheep] Atti della Societa Italiana delle Scienze Veterinarie 35:571-572, 1982.
1980 Nguyen, T.C., Bunch, T.D. :
Blood groups and evolutionary relationships among domestic sheep (Ovis aries), domestic goat (Capra hircus), aoudad (Ammotragus lervia) and european mouflon (Ovis musimon) Annales de Genetique et de Selection Animale 12:169-180, 1980.
1972 Agar, N.S., Evans, J.V., Roberts, J. :
Red blood cell potassium and haemoglobin polymorphism in sheep: a review Animal Breeding Abstracts 40:407-436, 1972.

Edit History


  • Created by Frank Nicholas on 06 Sep 2005
  • Changed by Frank Nicholas on 15 May 2020