OMIA:000424-9685 : Goitre, familial in Felis catus (domestic cat) |
In other species: chicken , dog , American black bear , pig , taurine cattle , goat , sheep , golden hamster , bongo , water buffalo
Categories: Endocrine / exocrine gland phene (incl mammary gland)
Possibly relevant human trait(s) and/or gene(s)s (MIM numbers): 274700 (trait) , 188450 (gene)
Links to MONDO diseases:
Mendelian trait/disorder: unknown
Considered a defect: yes
Cross-species summary: Goitre is the enlargement of the thyroid gland, causing a swelling in the front of the neck. The condition can develop due to nutritional iodine deficiencies but familial forms of this disorder have been identified in several species. The molecular basis been determined for familial goitre in cattle and goats. Also spelt goiter.
Genetic engineering:
Unknown
Have human generated variants been created, e.g. through genetic engineering and gene editing
Cite this entry
Nicholas, F. W., Tammen, I., & Sydney Informatics Hub. (2005). OMIA:000424-9685: Online Mendelian Inheritance in Animals (OMIA) [dataset]. https://omia.org/. https://doi.org/10.25910/2AMR-PV70
References
Note: the references are listed in reverse chronological order (from the most recent year to the earliest year), and alphabetically by first author within a year.
| 2020 | Iturriaga, M.P., Cocio, J.A., Barrs, V.R. : |
| Cluster of cases of congenital feline goitrous hypothyroidism in a single hospital. J Small Anim Pract 61:696-703, 2020. Pubmed reference: 32974927. DOI: 10.1111/jsap.13231. | |
| 1992 | Jones, B.R., Gruffydd-Jones, T.J., Sparkes, A.H., Lucke, V.M. : |
| Preliminary Studies on Congenital Hypothyroidism in a Family of Abyssinian Cats Veterinary Record 131:145-148, 1992. Pubmed reference: 1329305. | |
| 1991 | Sjollema, B.E., Denhartog, M.T., de Vijlder, J.J.M., Vandijk, J.E., Rijnberk, A. : |
| Congenital Hypothyroidism in Two Cats Due to Defective Organification - Data Suggesting Loosely Anchored Thyroperoxidase Acta Endocrinologica 125:435-440, 1991. Pubmed reference: 1659766. |
Edit History
- Created by Frank Nicholas on 06 Sep 2005