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OMIA:000350-9031 : Eudiplopodia in Gallus gallus (chicken)

Categories: Limbs / fins / digit / tail phene

Links to MONDO diseases: No links.

Mendelian trait/disorder: yes

Mode of inheritance: Autosomal recessive

Considered a defect: yes

Key variant known: no

Species-specific symbol: eu

Mapping: Robb et al. (2011) mapped this trait to chromosome GGA 5q (25,679,935 - 26,751,804)

Genetic engineering: Unknown
Have human generated variants been created, e.g. through genetic engineering and gene editing

Clinical features: "Homozygotes (-/-) have extra digits (5-9) on the dorsal surfaces of the limb buds, which develop into extra, scaled bidorsal toes on the feet with conical nails and occasional dorsal knobs or digits on the wings; expression is variable; temperature sensitive phenotype" (Robb et al., 2011)

Cite this entry

Nicholas, F. W., Tammen, I., & Sydney Informatics Hub. (2022). OMIA:000350-9031: Online Mendelian Inheritance in Animals (OMIA) [dataset]. https://omia.org/. https://doi.org/10.25910/2AMR-PV70

References

Note: the references are listed in reverse chronological order (from the most recent year to the earliest year), and alphabetically by first author within a year.

2011 Robb, EA., Gitter, CL., Cheng, HH., Delany, ME. :
Chromosomal mapping and candidate gene discovery of chicken developmental mutants and genome-wide variation analysis of MHC congenics. J Hered 102:141-56, 2011. Pubmed reference: 21273214. DOI: 10.1093/jhered/esq122.
1993 Abbott, UK., Pisenti, JM. :
Making the connection: exploring classical concepts in normal and abnormal limb development using contemporary approaches. Prog Clin Biol Res 383A:99-112, 1993. Pubmed reference: 8302913.
1986 Carrington, JL., Fallon, JF. :
Experimental manipulation leading to induction of dorsal ectodermal ridges on normal limb buds results in a phenocopy of the Eudiplopodia chick mutant. Dev Biol 116:130-7, 1986. Pubmed reference: 3732603.
1971 Fraser, RA., Abbott, UK. :
Studies on limb morphogenesis. V. The expression of Eudiplopodia and its experimental modification. J Exp Zool 176:219-36, 1971. Pubmed reference: 5559229. DOI: 10.1002/jez.1401760208.
Fraser, RA., Abbott, UK. :
Studies on limb morphogenesis. VI. Experiments with early stages of the polydactylous mutant Eudiplopodia. J Exp Zool 176:237-48, 1971. Pubmed reference: 5559230. DOI: 10.1002/jez.1401760209.
1964 Goetinck, PF. :
Studies on limb morphogenesis. II. Experiments with the polydactylous mutant eudiplopodia Dev Biol 10:71-91, 1964. Pubmed reference: 14206971.
1959 Rosenblatt, L.S., Kreutziger, G.O., Taylor, L.W. :
Eudiplopodia Poultry Science 38:1242 only, 1959.

Edit History


  • Created by Frank Nicholas on 26 Feb 2011
  • Changed by Imke Tammen2 on 22 Oct 2022