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OMIA:001225-9796 : Laminitis in Equus caballus (horse)

In other species: ass (donkey) , taurine cattle

Categories: Limbs / fins / digit / tail phene

Links to MONDO diseases: No links.

Mendelian trait/disorder: unknown

Considered a defect: yes

Species-specific description: See also 'OMIA:001898-9796 : Metabolic syndrome in Equus caballus'

Genetic engineering: Unknown
Have human generated variants been created, e.g. through genetic engineering and gene editing

Cite this entry

Nicholas, F. W., Tammen, I., & Sydney Informatics Hub. (2023). OMIA:001225-9796: Online Mendelian Inheritance in Animals (OMIA) [dataset]. https://omia.org/. https://doi.org/10.25910/2AMR-PV70

References

Note: the references are listed in reverse chronological order (from the most recent year to the earliest year), and alphabetically by first author within a year.

2023 Al-Ansari, A.S., Golding, E., Walshe, N., Mooney, C.T., Duggan, V. :
Obesity and obesity-associated metabolic disease conditions in Connemara ponies in Ireland. Equine Vet J , 2023. Pubmed reference: 37985219. DOI: 10.1111/evj.14029.
Clark, B.L., Stewart, A.J., Kemp, K.L., Bamford, N.J., Bertin, F.R. :
Evaluation of field-testing protocols to diagnose insulin dysregulation in ponies using a Bayesian approach. Vet J :106019, 2023. Pubmed reference: 37536451. DOI: 10.1016/j.tvjl.2023.106019.
Elliott, J., Bailey, S.R. :
A review of cellular and molecular mechanisms in endocrinopathic, sepsis-related and supporting limb equine laminitis. Equine Vet J 55:350-375, 2023. Pubmed reference: 36847165. DOI: 10.1111/evj.13933.
Kellon, E.M., Gustafson, K.M. :
Hypertriglyceridemia in equines with refractory hyperinsulinemia treated with SGLT2 inhibitors. Open Vet J 13:365-375, 2023. Pubmed reference: 37026076. DOI: 10.5455/OVJ.2023.v13.i3.14.
Lykkjen, S., Stenbakk, L.K., Holmøy, I.H. :
Prevalence and risk factors for laminitis within the Norwegian pony breed Nordlandshest/Lyngshest. Acta Vet Scand 65:22, 2023. Pubmed reference: 37328910. DOI: 10.1186/s13028-023-00687-w.
McGowan, C.M., Ireland, J.L. :
Equine endocrine disease: Challenges with case definition for research. J Equine Vet Sci 124:104491, 2023. Pubmed reference: 37236726. DOI: 10.1016/j.jevs.2023.104491.
Moss, A., Leise, B., Hackett, E. :
Stress response as a contributing factor in horses with laminitis. J Vet Sci 24:e33, 2023. Pubmed reference: 37012040. DOI: 10.4142/jvs.22039.
2021 Ireland, J.L., McGowan, C.M. :
Translating research into practice: Adoption of endocrine diagnostic testing in cases of equine laminitis. Vet J 272:105656, 2021. Pubmed reference: 33941328. DOI: 10.1016/j.tvjl.2021.105656.
Yang, Q., Lopez, M.J. :
The equine hoof: Laminitis, progenitor (stem) cells, and therapy development. Toxicol Pathol 49:1294-1307, 2021. Pubmed reference: 31741428. DOI: 10.1177/0192623319880469.
2020 Wallis, N., Raffan, E. :
The genetic basis of obesity and related metabolic diseases in humans and companion animals. Genes 11:1378, 2020. Pubmed reference: 33233816. DOI: 10.3390/genes11111378.
2019 Pollard, D., Wylie, C.E., Newton, J.R., Verheyen, K.L.P. :
Incidence and clinical signs of owner-reported equine laminitis in a cohort of horses and ponies in Great Britain. Equine Vet J 51:587-594, 2019. Pubmed reference: 30516850. DOI: 10.1111/evj.13059.
2016 Welsh, C.E., Duz, M., Parkin, T.D., Marshall, J.F. :
Prevalence, survival analysis and multimorbidity of chronic diseases in the general veterinarian-attended horse population of the UK. Prev Vet Med 131:137-45, 2016. Pubmed reference: 27544263. DOI: 10.1016/j.prevetmed.2016.07.011.
Wylie, C.E., Shaw, D.J., Verheyen, K.L., Newton, J.R. :
Decision-tree analysis of clinical data to aid diagnostic reasoning for equine laminitis: a cross-sectional study. Vet Rec , 2016. Pubmed reference: 26969668. DOI: 10.1136/vr.103588.
2014 Karikoski, N.P., McGowan, C.M., Singer, E.R., Asplin, K.E., Tulamo, R.M., Patterson-Kane, J.C. :
Pathology of Natural Cases of Equine Endocrinopathic Laminitis Associated With Hyperinsulinemia. Vet Pathol , 2014. Pubmed reference: 25232034. DOI: 10.1177/0300985814549212.
2013 Steelman, S.M., Johnson, D., Wagner, B., Stokes, A., Chowdhary, B.P. :
Cellular and humoral immunity in chronic equine laminitis. Vet Immunol Immunopathol 153:217-26, 2013. Pubmed reference: 23521925. DOI: 10.1016/j.vetimm.2013.03.001.
Wylie, C.E., Collins, S.N., Verheyen, K.L., Newton, J.R. :
Risk factors for equine laminitis: A case-control study conducted in veterinary-registered horses and ponies in Great Britain between 2009 and 2011. Vet J , 2013. Pubmed reference: 24070987. DOI: 10.1016/j.tvjl.2013.08.028.
Zamboulis, D.E., Senior, M., Clegg, P.D., Milner, P.I. :
Expression of purinergic P2X receptor subtypes 1, 2, 3 and 7 in equine laminitis. Vet J , 2013. Pubmed reference: 24080476. DOI: 10.1016/j.tvjl.2013.08.017.
2012 Hampson, B., de Laat, M., Beausac, C., Rovel, T., Pollitt, C. :
Histopathological examination of chronic laminitis in Kaimanawa feral horses of New Zealand. N Z Vet J , 2012. Pubmed reference: 22621688. DOI: 10.1080/00480169.2012.682271.
Katz, L.M., Bailey, S.R. :
A review of recent advances and current hypotheses on the pathogenesis of acute laminitis. Equine Vet J 44:752-61, 2012. Pubmed reference: 23106629. DOI: 10.1111/j.2042-3306.2012.00664.x.
Steelman, S.M., Chowdhary, B.P. :
Plasma proteomics shows an elevation of the anti-inflammatory protein APOA-IV in chronic equine laminitis. BMC Vet Res 8:179, 2012. Pubmed reference: 23016951. DOI: 10.1186/1746-6148-8-179.
Steelman, S.M., Chowdhary, B.P., Dowd, S., Suchodolski, J., Jane Ka, J.E. :
Pyrosequencing of 16S rRNA genes in fecal samples reveals high diversity of hindgut microflora in horses and potential links to chronic laminitis. BMC Vet Res 8:231, 2012. Pubmed reference: 23186268. DOI: 10.1186/1746-6148-8-231.
Valle, E., Storace, D., Sanguineti, R., Carter, R., Odetti, P., Geor, R., Bergero, D. :
Association of the glycoxidative stress marker pentosidine with equine laminitis. Vet J , 2012. Pubmed reference: 23206662. DOI: 10.1016/j.tvjl.2012.10.030.
Wylie, C.E. :
Equine laminitis: What is all the hype about hyperinsulinaemic laminitis? Vet J , 2012. Pubmed reference: 23168265. DOI: 10.1016/j.tvjl.2012.10.005.
2011 de la Rebière de Pouyade, G., Serteyn, D. :
The role of activated neutrophils in the early stage of equine laminitis. Vet J 189:27-33, 2011. Pubmed reference: 20655252. DOI: 10.1016/j.tvjl.2010.06.008.
Harris, P. :
Laminitis after 2000years: Adding bricks to our wall of knowledge. Vet J , 2011. Pubmed reference: 22036868. DOI: 10.1016/j.tvjl.2011.09.014.
Hertsch, B., Teschner, D. :
[Growth of the hoof horn in horses with chronic laminitis]. Tierarztl Prax Ausg G Grosstiere Nutztiere 39:163-70, 2011. Pubmed reference: 22138801.
Mitchell, J.D., Elliott, J. :
Towards a new treatment for equine acute laminitis: The importance of signalling pathways. Vet J , 2011. Pubmed reference: 22093910. DOI: 10.1016/j.tvjl.2011.10.011.
Wylie, C.E., Collins, S.N., Verheyen, K.L., Newton, J.R. :
Risk factors for equine laminitis: A systematic review with quality appraisal of published evidence. Vet J , 2011. Pubmed reference: 22104504. DOI: 10.1016/j.tvjl.2011.10.020.
Wylie, CE., Collins, SN., Verheyen, KL., Richard Newton, J. :
Frequency of equine laminitis: A systematic review with quality appraisal of published evidence. Vet J , 2011. Pubmed reference: 21665498. DOI: 10.1016/j.tvjl.2011.04.014.
2010 Brooks, SA., Bailey, E. :
RT-qPCR comparison of mast cell populations in whole blood from healthy horses and those with laminitis. Anim Genet 41 Suppl 2:16-22, 2010. Pubmed reference: 21070271. DOI: 10.1111/j.1365-2052.2010.02093.x.
2009 Faleiros, RR., Leise, BB., Westerman, T., Yin, C., Nuovo, GJ., Belknap, JK. :
In vivo and in vitro evidence of the involvement of CXCL1, a keratinocyte-derived chemokine, in equine laminitis. J Vet Intern Med 23:1086-96, 2009. Pubmed reference: 19572911. DOI: 10.1111/j.1939-1676.2009.0349.x.
2008 Brown, PA., Bodles-Brakhop, A., Draghia-Akli, R. :
Plasmid growth hormone releasing hormone therapy in healthy and laminitis-afflicted horses-evaluation and pilot study. Journal of Gene Medicine 10:564-74, 2008. Pubmed reference: 18302303. DOI: 10.1002/jgm.1170.
2005 Hansen, N., Buchner, HH., Haller, J., Windischbauer, G. :
Evaluation using hoof wall strain gauges of a therapeutic shoe and a hoof cast with a heel wedge as potential supportive therapy for horses with laminitis. Vet Surg 34:630-6, 2005. Pubmed reference: 16343152. DOI: 10.1111/j.1532-950X.2005.00023.x.
Kuwano, A., Ueno, T., Katayama, Y., Nishiyama, T., Arai, K. :
Unilateral basement membrane zone alteration of the regenerated laminar region in equine chronic laminitis. J Vet Med Sci 67:685-91, 2005. Pubmed reference: 16082116.
2004 Bailey, SR. :
The pathogenesis of acute laminitis: fitting more pieces into the puzzle. Equine Vet J 36:199-203, 2004. Pubmed reference: 15147124.
Berhane, Y., Bailey, SR., Harris, PA., Griffiths, MJ., Elliott, J. :
In vitro and in vivo studies of homocysteine in equine tissues: implications for the pathophysiology of laminitis. Equine Vet J 36:279-84, 2004. Pubmed reference: 15147138.
French, KR., Pollitt, CC. :
Equine laminitis: loss of hemidesmosomes in hoof secondary epidermal lamellae correlates to dose in an oligofructose induction model: an ultrastructural study. Equine Vet J 36:230-5, 2004. Pubmed reference: 15147130.
French, KR., Pollitt, CC. :
Equine laminitis: cleavage of laminin 5 associated with basement membrane dysadhesion. Equine Vet J 36:242-7, 2004. Pubmed reference: 15147132.
French, KR., Pollitt, CC. :
Equine laminitis: glucose deprivation and MMP activation induce dermo-epidermal separation in vitro. Equine Vet J 36:261-6, 2004. Pubmed reference: 15147135.
French, KR., Pollitt, CC. :
Equine laminitis: congenital, hemidesmosomal plectin deficiency in a Quarter Horse foal. Equine Vet J 36:299-303, 2004. Pubmed reference: 15147142.
Kyaw-Tanner, M., Pollitt, CC. :
Equine laminitis: increased transcription of matrix metalloproteinase-2 (MMP-2) occurs during the developmental phase. Equine Vet J 36:221-5, 2004. Pubmed reference: 15147128.
Mobasheri, A., Critchlow, K., Clegg, PD., Carter, SD., Canessa, CM. :
Chronic equine laminitis is characterised by loss of GLUT1, GLUT4 and ENaC positive laminar keratinocytes. Equine Vet J 36:248-54, 2004. Pubmed reference: 15147133.
Moore, RM., Eades, SC., Stokes, AM. :
Evidence for vascular and enzymatic events in the pathophysiology of acute laminitis: which pathway is responsible for initiation of this process in horses? Equine Vet J 36:204-9, 2004. Pubmed reference: 15147125.
van Eps, AW., Pollitt, CC. :
Equine laminitis: cryotherapy reduces the severity of the acute lesion. Equine Vet J 36:255-60, 2004. Pubmed reference: 15147134.
2003 Wagner, I.P., Rees, C.A., Dunstan, R.W., Credille, K.M., Hood, D.M. :
Evaluation of systemic immunologic hyperreactivity after intradermal testing in horses with chronic laminitis American Journal of Veterinary Research 64:279-83, 2003. Pubmed reference: 12661866.
2002 Anon. :
Laminitis research Journal of Equine Veterinary Science 22:23, 2002.
Dunne, K., Prendergast, M., McAllister, H. :
Equine laminitis: A clinical guide to diagnosis and treatment Irish Veterinary Journal 55:322-332, 2002.
Hunt, R.J. :
Laminitis in the geriatric horse Veterinary Clinics of North America - Equine Practice 18:439-52, 2002.
Kuwano, A., Katayama, Y., Kasashima, Y., Okada, K., Reilly, J.D. :
A gross and histopathological study of an ectopic white line development in equine laminitis Journal of Veterinary Medical Science 64:893-900, 2002. Pubmed reference: 12419865.
Taylor, D., Hood, D.M., Wagner, I.P. :
Short-term effect of therapeutic shoeing on severity of lameness in horses with chronic laminitis American Journal of Veterinary Research 63:1629-33, 2002. Pubmed reference: 12492275.
2001 Belknap, J. :
Medical treatment options in equine laminitis Compendium on Continuing Education for the Practicing Veterinarian 23:918-921, 2001.
Wisniewski, E., Dabrowska, J. :
Treatment of acute equine laminitis Medycyna Weterynaryjna 57:779-782, 2001.
2000 Hilsenroth, R. :
Helping horses with chronic laminitis Equine Practice 22:32, 2000.
Moyer, W.A. :
Is there a best treatment for laminitis? Compendium on Continuing Education for the Practicing Veterinarian 22:500-502, 2000.
1999 Cripps, P.J., Eustace, R.A. :
Radiological measurements from the feet of normal horses with relevance to laminitis Equine Veterinary Journal 31:427-432, 1999. Pubmed reference: 10505960.
Cripps, P.J., Eustace, R.A. :
Factors involved in the prognosis of equine laminitis in the UK Equine Veterinary Journal 31:433-442, 1999. Pubmed reference: 10505961.
Hood, D.M. :
Laminitis - Preface Veterinary Clinics of North America - Equine Practice 15:XI-XII, 1999.
Hood, D.M. :
Laminitis in the horse Veterinary Clinics of North America - Equine Practice 15:287-+, 1999.
Hood, D.M. :
Laminitis as a systemic disease Veterinary Clinics of North America - Equine Practice 15:481-+, 1999.
Hood, D.M. :
The pathophysiology of developmental and acute laminitis Veterinary Clinics of North America - Equine Practice 15:321-+, 1999.
Katwa, L.C., Johnson, P.J., Ganjam, V.K., Kreeger, J.M., Messer, N.T. :
Expression of endothelin in equine laminitis Equine Veterinary Journal 31:243-247, 1999. Pubmed reference: 10402139.
Lopez, H.S., Sepulveda, M.L.H., Brumbaugh, G.W. :
Pharmacologic and alternative therapies for the horse with chronic laminitis Veterinary Clinics of North America - Equine Practice 15:495-+, 1999.
Swanson, T.D. :
Clinical presentation, diagnosis, and prognosis of acute laminitis Veterinary Clinics of North America - Equine Practice 15:311-+, 1999.
Wagner, I.P., Heymering, H. :
Historical perspectives on laminitis Veterinary Clinics of North America - Equine Practice 15:295-+, 1999.
1998 Robinson, N.E. :
Step by painful step - increasing knowledge about laminitis Equine Veterinary Journal 30:89-90, 1998. Pubmed reference: 9535061.
1997 Anon. :
Laminitis Journal of Equine Veterinary Science 17:131, 1997.
Polzer, J., Slater, M.R. :
Age, breed, sex and seasonality as risk factors for equine laminitis Preventive Veterinary Medicine 29:179-184, 1997. Pubmed reference: 9234403.
Strasser, H. :
New aspects of laminitis in horses [German] Tierarztliche Umschau 52:190-194, 1997.
Weiss, D.J. :
Equine laminitis - a review of recent research Equine Practice 19:16-20, 1997.
1996 Anon. :
Client information series - laminitis Equine Practice 18:31-34, 1996.
1995 Dalin, G. :
Control of genetically determined diseases and defects in Swedish horse breeding Equine Veterinary Journal 27:411-415, 1995.
Riber, C., Rubio, M.D., Marquez, F., Pinedo, M., Munoz, A., Castejon, F. :
Haematological changes observed in andalusian horses with laminitis Journal of Veterinary Medical Science 57:981-984, 1995. Pubmed reference: 8593320.
Slater, M.R., Hood, D.M., Carter, G.K. :
Descriptive epidemiological study of equine laminitis Equine Veterinary Journal 27:364-367, 1995. Pubmed reference: 8654351.

Edit History


  • Created by Frank Nicholas on 06 Sep 2005
  • Changed by Imke Tammen2 on 29 May 2023