In other species: dog , brown bear , domestic cat , greater Indian rhinoceros , taurine cattle , Indo-pacific bottlenose dolphin

Categories: Nervous system phene

Possibly relevant human trait(s) and/or gene(s)s (MIM numbers): 182940 (trait) , 206500 (trait) , 301410 (trait) , 619452 (trait)

Links to MONDO diseases: No links.

Mendelian trait/disorder: unknown

Considered a defect: yes

Cross-species summary: Congenital absence of the cranial vault, with the cerebral hemispheres completely missing or reduced to small masses. This phene was originally called anencephaly, but a recent review suggested that the term anencephaly/exencephaly is more appropriate.

Genetic engineering: Unknown
Have human generated variants been created, e.g. through genetic engineering and gene editing