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OMIA:000247-9685 : Cushing syndrome, ACTH-dependent, pituitary-dependent hyperadrenocorticism in Felis catus (domestic cat)

In other species: dog , Grevy's zebra , Przewalski's horse , plains zebra

Categories: Endocrine / exocrine gland phene (incl mammary gland)

Links to possible relevant human trait(s) and/or gene(s) in OMIM: 160980 (trait) , 219080 (trait) , 219090 (trait)

Single-gene trait/disorder: unknown

Disease-related: yes

Cross-species summary: Entries for this type of Cushing syndrome (pituitary-dependent hyperadrenocorticism, pituitary pars intermedia dysfunction (PPID)) are included for some species under the phene 'Cushing syndrome, generic' (previously 'Hyperadrenocorticism, generic'): OMIA:000494. Renamed from 'Cushing disease, pituitary-dependent hyperadrenocorticism' to 'Cushing syndrome, ACTH-dependent, pituitary-dependent hyperadrenocorticism based on ALIVE recommendations (PMID:40872711), with the following definiton:  "Hypercortisolism occurs due to dysregulated ACTH secretion by the pituitary. This is generally associated with pituitary neoplasia or hyperplasia"  

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Cite this entry

Nicholas, F. W., Tammen, I., & Sydney Informatics Hub. (2005). OMIA:000247-9685: Online Mendelian Inheritance in Animals (OMIA) [dataset]. https://omia.org/. https://doi.org/10.25910/2AMR-PV70

References

Note: the references are listed in reverse chronological order (from the most recent year to the earliest year), and alphabetically by first author within a year.

2025 Niessen, S.J.M., Behrend, E.N., Fracassi, F., Church, D.B., Foster, S.F., Galac, S., Melian, C., Pöppl, Á.G., Ramsey, I.K., Sieber-Ruckstuhl, N.S. :
Agreeing Language in Veterinary Endocrinology (ALIVE): Cushing's syndrome and hypoadrenocorticism-A modified Delphi-method-based system to create consensus definitions. Vet Sci 12:761, 2025. Pubmed reference: 40872711. DOI: 10.3390/vetsci12080761.
2023 Hardy, L., Gil-Morales, C., Maunder, C., Paran, E. :
Skin fragility in a cat presenting with pituitary-dependent hyperadrenocorticism. JFMS Open Rep 9:20551169231171245, 2023. Pubmed reference: 37360386. DOI: 10.1177/20551169231171245.
2001 Meij, B.P. :
Hypophysectomy as a treatment for canine and feline Cushing's disease Veterinary Clinics of North America - Small Animal Practice 31:1015-+, 2001.
1999 Schaer, M., Ginn, P.E. :
Iatrogenic Cushing's syndrome and steroid hepatopathy in a cat Journal of the American Animal Hospital Association 35:48-51, 1999. Pubmed reference: 9934928.
1994 Feldman, E.C., Nelson, R.W. :
Comparative aspects of Cushing's syndrome in dogs and cats Endocrinology and Metabolism Clinics of North America 23:671-691, 1994. Pubmed reference: 7805662.

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  • Created by Frank Nicholas on 06 Sep 2005