OMIA:000425-9940 : Haemonchus contortus, resistance to (Golden ram effect) in Ovis aries

Categories: Immune system phene

Links to MONDO diseases: No links.

Mendelian trait/disorder: unknown

Considered a defect: no

Species-specific description: In a large-scale investigation of the quantitative genetics of resistance and resiliance to Haemonchus contortus in Merino sheep, Albers et al. (1987) observed one 'outlier' sire (dubbed the "golden ram") whose progeny exhibited extremely high resistance. The evidence justified a tentative conclusion that this sire was carrying a major gene for resistance. Unfortunately, such a gene failed to materialise in studies of subsequent generations.

References

Note: the references are listed in reverse chronological order (from the most recent year to the earliest year), and alphabetically by first author within a year.

1987 Albers, G.A.A., Gray, G.D., Piper, L.R., Barker, J.S.F., Le Jambre, L.F., Barger, I.A. :
The genetics of resistance and resilience to Haemonchus contortus infection in young Merino sheep International Journal for Parasitology 17:1355-1363, 1987. Pubmed reference: 3429127 .
Gray, G.D. :
Genetic resistance to haemonchosis in sheep Parasitology Today 3:253-255, 1987.

Edit History


  • Created by Frank Nicholas on 06 Sep 2005
  • Changed by Frank Nicholas on 21 May 2012
  • Changed by Frank Nicholas on 20 Aug 2020