OMIA:000483-9915 : Polled/Horns in Bos indicus
In other species: cattle , goat , sheep , domestic yak , bighorn sheep , water buffalo , kouprey
Categories: Craniofacial phene
Possibly relevant human trait(s) and/or gene(s) (MIM number): 110100 (trait)
Links to MONDO diseases: No links.
Mendelian trait/disorder: unknown
Considered a defect: no
Cross-species summary: Horns are paired appendages with a bony core that is attached to the skull and a keratin outer sheath. There is substantial variation in the extent of horn growth, making classification difficult. However, in general, the presence or absence of horns can be attributed to the action of two alleles at an autosomal locus. The type of gene action varies considerably between and among species. Absence of horns is called 'polled'. See also entries for 'scurs'.
Molecular basis: By whole-genome sequencing with an Oxford Nanopore Technology's minION sequencer "four homozygous poll (PcPc), four homozygous horned (pp) and three heterozygous (Pcp) Brahmans" and comparing the sequence in the polled region, Lamb et al. (2020) confirmed that the polled allele in the Brahman breed is the Celtic allele. See 'OMIA 000483-9913 : Polled/Horns in Bos taurus' information on the variant.
Note: the references are listed in reverse chronological order (from the most recent year to the earliest year), and alphabetically by first author within a year.
|2023||Aldersey, J.E., Liu, N., Tearle, R., Low, W.Y., Breen, J., Williams, J.L., Bottema, C.D.K. :|
|Topologically associating domains in the POLLED region are the same for Angus- and Brahman-specific Hi-C reads from F1 hybrid fetal tissue. Anim Genet :, 2023. Pubmed reference: 36990727 . DOI: 10.1111/age.13322.|
|2020||Lamb, H.J., Ross, E.M., Nguyen, L.T., Lyons, R.E., Moore, S.S., Hayes, B.J. :|
|Short Communication: Characterisation of the poll allele in Brahman cattle using long read Oxford Nanopore sequencing. J Anim Sci 98:skaa127, 2020. Pubmed reference: 32318708 . DOI: 10.1093/jas/skaa127.|
- Created by Imke Tammen2 on 10 Feb 2023
- Changed by Imke Tammen2 on 10 Feb 2023