Categories: Endocrine / exocrine gland phene (incl mammary gland)

Possible human homologues (MIM numbers): 169170 (trait) , 201710 (trait)

Cross-species summary: Cushing syndrome (or hyperadrenocorticism) refers to a group of clinical syndromes that are caused by a chronic excess of glucocorticoid activity, which can be due to a range of endogenous (e.g., genetic or neoplasms) or exogenous (iatrogenic) steroid hormones. (Modified from ALIVE recommendations (PMID:40872711). Entries for Cushing syndrome - ACTH-Dependent—Pituitary-Dependent Hypercortisolism Cushing syndrome may be included here and for some species also under OMIA:000247. Renamed from 'Hyperadrenocorticism, generic' to 'Cushing syndrome, generic' [10/09/2025].

Species in which this phene is found:
dog (Canis lupus familiaris)
domestic ferret (Mustela putorius furo)
domestic cat (Felis catus)
domestic horse (Equus caballus)
rabbit (Oryctolagus cuniculus)
golden hamster (Mesocricetus auratus)
domestic guinea pig (Cavia porcellus)