You are here: OMIA / Search / OMIA:000556 / Atlantic salmon

OMIA:000556-8030 : Immunoglobulin M deficiency in Salmo salar (Atlantic salmon)

In other species: domestic horse

Categories: Immune system phene

Links to possible relevant human trait(s) and/or gene(s) in OMIM: 308250 (trait)

Single-gene trait/disorder: yes

Disease-related: unknown

Key variant known: no

Species summary: Raudstein et al. (2025) "used CRISPR/Cas9 technology to knock out the two IgM genes in Atlantic salmon." This study involves gene edited or genetically modified organisms (GMO). 

Genetic engineering: Yes - variants have been created artificially, e.g. by genetic engineering or gene editing
Have human generated variants been created, e.g. through genetic engineering and gene editing

Contact us

If you notice anything missing or in need of change, please contact us at: [email protected].

Cite this entry

Nicholas, F. W., Tammen, I., & Sydney Informatics Hub. (2026). OMIA:000556-8030: Online Mendelian Inheritance in Animals (OMIA) [dataset]. https://omia.org/. https://doi.org/10.25910/2AMR-PV70

Reference

2025 Raudstein, M., Peñaranda, M.M.D., Kjærner-Semb, E., Grove, S., Morton, H.C., Edvardsen, R.B. :
Generation of IgM+ B cell-deficient Atlantic salmon (Salmo salar) by CRISPR/Cas9-mediated IgM knockout. Sci Rep 15:3599, 2025. Pubmed reference: 39875802. DOI: 10.1038/s41598-025-87658-5.

Edit History


  • Created by Imke Tammen2 on 07 Jan 2026
  • Changed by Imke Tammen2 on 07 Jan 2026