OMIA:000586-9615 : Legg-Calvé-Perthes disease in Canis lupus familiaris (dog)

In other species: crab-eating macaque , Rhesus monkey , lesser panda , goat

Categories: Skeleton phene (incl. short stature & teeth)

Links to possible relevant human trait(s) and/or gene(s) in OMIM: 150600 (trait)

Mendelian trait/disorder: yes

Considered a defect: yes

Key variant known: no

Cite this entry

Nicholas, F. W., Tammen, I., & Sydney Informatics Hub. (2005). OMIA:000586-9615: Online Mendelian Inheritance in Animals (OMIA) [dataset].


Note: the references are listed in reverse chronological order (from the most recent year to the earliest year), and alphabetically by first author within a year.

2023 Hayward, J.J., Todhunter, R.J. :
Common orthopedic traits and screening for breeding programs. Vet Clin North Am Small Anim Pract 53:1013-1029, 2023. Pubmed reference: 37225647. DOI: 10.1016/j.cvsm.2023.04.004.
2012 Starr-Moss, A.N., Nowend, K.L., Alling, K.M., Zepp, E.J., Murphy, K.E. :
Exclusion of COL2A1 in canine Legg-Calvé-Perthes disease Anim Genet 43:112-3, 2012. Pubmed reference: 22221034. DOI: 10.1111/j.1365-2052.2011.02215.x.
2009 Scherzer, C., Windhagen, H., Nellesen, J., Crostack, H.A., Crostak, H.A., Rohn, K., Witte, F., Thorey, F., Fehr, M., Hauschild, G. :
Comparative structural analysis of the canine femoral head in Legg-Calvé-Perthes disease. Vet Radiol Ultrasound 50:404-11, 2009. Pubmed reference: 19697606.
2005 Demko, J., McLaughlin, R. :
Developmental orthopedic disease. Vet Clin North Am Small Anim Pract 35:1111-35, v, 2005. Pubmed reference: 16129135. DOI: 10.1016/j.cvsm.2005.05.002.
Isola, M., Zotti, A., Carnier, P., Baroni, E., Busetto, R. :
Dual-energy X-ray absorptiometry in canine Legg-Calvé-Perthes disease. J Vet Med A Physiol Pathol Clin Med 52:407-10, 2005. Pubmed reference: 16176571. DOI: 10.1111/j.1439-0442.2005.00746.x.
2002 LaFond, E., Breur, G.J., Austin, C.C. :
Breed susceptibility for developmental orthopedic diseases in dogs Journal of the American Animal Hospital Association 38:467-477, 2002. Pubmed reference: 12220032.
1999 Brenig, B., Leeb, T., Jansen, S., Kopp, T. :
Analysis of blood clotting factor activities in canine Legg-Calvé-Perthes' disease. J Vet Intern Med 13:570-3, 1999. Pubmed reference: 10587258.
1998 Brunnberg, L., Allgoewer, I., Perslow, M.B. :
Total hip replacement (mini tep) in small toy breeds - first clinical results [German] Kleintierpraxis 43:655 ff., 1998.
1995 Engelke, A., Westhoff, A., Meyerlindenberg, A., Fehr, M., Dammrich, K., Nolte, I. :
The Technique of Scintigraphy - A Picture Giving Method by Case Example of Morbus Legg-Calve-Perthes in the Dog Kleintierpraxis 40:49-54, 1995.
1992 Robinson, R. :
Legg-Calve-Perthes Disease in Dogs - Genetic Aetiology J Small Anim Pract 33:275-276, 1992.
1990 Eichelberg, H., Pohl, U. :
Synopsis of Literature - Legg-Perthes Disease Kleintierpraxis 35:83-84, 1990.
1989 Vasseur, P.B., Foley, P., Stevenson, S., Heitter, D. :
Mode of Inheritance of Perthes Disease in Manchester Terriers Clinical Orthopaedics and Related Research :281-292, 1989. Pubmed reference: 2743671.
1981 Mickelson, M.R., McCurnin, D.M., Awbrey, B.J., Maynard, J.A., Martin, R.K. :
Legg-Calvé-Perthes disease in dogs: a comparison to human Legg-Culvé-Perthes disease. Clin Orthop Relat Res :287-300, 1981. Pubmed reference: 7249458.
1978 Pidduck, H., Webbon, P.M. :
The genetic control of Perthes' disease in Toy Poodles - a working hypothesis Journal of Small Animal Practice 19:729-733, 1978. Pubmed reference: 723237.
1972 Warren, DV., Dingwall, JS. :
Legg-Perthes disease in the dog--a review. Can Vet J 13:135-7, 1972. Pubmed reference: 5036901.
1971 Smith, K.W. :
Legg-Perthes disease Veterinary Clinics of North America 1:479-487, 1971. Pubmed reference: 4949795.
1970 Lee, R. :
A study of the radiographic and histological changes occurring in Legg-Calve-Perthes disease (LCP) in the dog. J Small Anim Pract 11:621-38, 1970. Pubmed reference: 5531150.
1969 Lee, R., Fry, P.D. :
Some observations on the occurance of Legg-Calvé-Perthes' disease (coxaplana) in the dog, and an evaluation of excision arthroplasty as a method of treatment. J Small Anim Pract 10:309-17, 1969. Pubmed reference: 5816741.
Ljunggren, G. :
Legg-Perthes disease in the dog. A case report with special reference to initial radiographic changes. Clin Orthop Relat Res 62:31-6, 1969. Pubmed reference: 5813190.
1967 Ljunggren, G. :
Legg-Perthes disease in the dog. Acta Orthop Scand :Suppl 95:1-79, 1967. Pubmed reference: 6020301.
Paatsama, S., Rissanen, P., Rokkanen, P. :
Legg-Perthes disease in the dog: an experimental study using the histological and histochemical methods, oxytetracycline bone labelling technique autoradiography and microradiography Journal of Small Animal Practice 8:215-220, 1967. Pubmed reference: 6068724.
1953 Anderson, W.D., Schlotthauer, C.F. :
Leggs-Perthes' disease, coxa plana, in the dogs. J Am Vet Med Assoc 122:115-6, 1953. Pubmed reference: 13022568.

Edit History

  • Created by Frank Nicholas on 06 Sep 2005