OMIA:000613-9796 : Lymphoedema in Equus caballus

In other species: dog , cattle

Categories: Immune system phene

Links to MONDO diseases: No links.

Mendelian trait/disorder: unknown

Considered a defect: yes

Cross-species summary: Lymphedema

Species-specific name: Chronic pastern dermatitis; chronic progressive lymphedema, equine pastern dermatitis

Species-specific symbol: CPD; CPL

Inheritance: De Keyser et al. (2014) estimated heritability to be 0.11 in Belgian Draught Horses of all ages, and 0.26 after excluding horses under 3 years of age.


Note: the references are listed in reverse chronological order (from the most recent year to the earliest year), and alphabetically by first author within a year.

2023 Gerber, V., Kaiser-Thom, S., Oesch, S. :
Equine pastern dermatitis: a narrative review on clinical presentation, diagnosis, risk factors, prevention, and therapeutic approaches. J Am Vet Med Assoc :1-8, 2023. Pubmed reference: 36917616 . DOI: 10.2460/javma.22.12.0569.
2015 de Keyser, K., Janssens, S., Buys, N. :
Chronic progressive lymphoedema in draught horses. Equine Vet J 47:260-6, 2015. Pubmed reference: 24593274 . DOI: 10.1111/evj.12256.
2014 De Keyser, K., Janssens, S., Peeters, L.M., Foqué, N., Gasthuys, F., Oosterlinck, M., Buys, N. :
Genetic parameters for chronic progressive lymphedema in Belgian Draught Horses. J Anim Breed Genet 131:522-528, 2014. Pubmed reference: 24641331 . DOI: 10.1111/jbg.12087.
2010 Mittmann, E.H., Mömke, S., Distl, O. :
Whole-genome scan identifies quantitative trait loci for chronic pastern dermatitis in German draft horses. Mamm Genome 21:95-103, 2010. Pubmed reference: 20039044 . DOI: 10.1007/s00335-009-9244-z.
2007 Mömke, S., Distl, O. :
Molecular genetic analysis of the ATP2A2 gene as candidate for chronic pastern dermatitis in German draft horses. J Hered 98:267-71, 2007. Pubmed reference: 17395600 . DOI: 10.1093/jhered/esm004.
2005 Geburek, F., Deegen, E., Hewicker-Trautwein, M., Ohnesorge, B. :
[The development of verrucous pastern dermatitis syndrome in heavy draught horses. Part I: Review of the literature] Dtsch Tierarztl Wochenschr 112:211-4, 2005. Pubmed reference: 16028485 .
Geburek, F., Ohnesorge, B., Deegen, E., Doeleke, R., Hewicker-Trautwein, M. :
Alterations of epidermal proliferation and cytokeratin expression in skin biopsies from heavy draught horses with chronic pastern dermatitis. Vet Dermatol 16:373-84, 2005. Pubmed reference: 16359304 . DOI: 10.1111/j.1365-3164.2005.00482.x.
2004 Wallraf, A., Hamann, H., Deegen, E., Ohnesorge, B., Distl, O. :
[Analysis of the prevalence of pastern dermatitis in German Coldblood horse breeds] Berl Munch Tierarztl Wochenschr 117:148-52, 2004. Pubmed reference: 15046463 .

Edit History

  • Created by Frank Nicholas on 01 Dec 2010
  • Changed by Frank Nicholas on 26 Mar 2014
  • Changed by Imke Tammen2 on 18 Mar 2023