OMIA:000710-9615 : Nephropathy in Canis lupus familiaris (dog)

In other species: pig , sheep

Categories: Renal / urinary system phene

Mendelian trait/disorder: unknown

Considered a defect: yes

Cross-species summary: Disease of the kidneys.

Species-specific name: References relating to chronic kidney disease are included in this entry.

Species-specific description: Information relating to autosomal recessive hereditary nephropathy due to COL4A4 variants have been moved to "OMIA:002618-9615 : Nephropathy, COL4A4 related in Canis lupus familiaris" [1/2/2023]

Breeds: Bernese Mountain Dog (Dog) (VBO_0200161), Boxer (Dog) (VBO_0200210), Dalmatian (Dog) (VBO_0200427), Pembroke Welsh Corgi (Dog) (VBO_0200995), Rottweiler (Dog) (VBO_0201143), Shih Tzu (Dog) (VBO_0201223), Weimaraner (Dog) (VBO_0201401).
Breeds in which the phene has been documented. (If a likely causal variant has been documented for the phene, see the variant table breeds in which the variant has been reported).

Cite this entry

Nicholas, F. W., Tammen, I., & Sydney Informatics Hub. (2023). OMIA:000710-9615: Online Mendelian Inheritance in Animals (OMIA) [dataset].


Note: the references are listed in reverse chronological order (from the most recent year to the earliest year), and alphabetically by first author within a year.

2023 Lingaas, F., Tengvall, K., Jansen, J.H., Pelander, L., Hurst, M.H., Meuwissen, T., Karlsson, Å., Meadows, J.R.S., Sundström, E., Thoresen, S.I., Arnet, E.F., Guttersrud, O.A., Kierczak, M., Hytönen, M.K., Lohi, H., Hedhammar, Å., Lindblad-Toh, K., Wang, C. :
Bayesian mixed model analysis uncovered 21 risk loci for chronic kidney disease in boxer dogs. PLoS Genet 19:e1010599, 2023. Pubmed reference: 36693108. DOI: 10.1371/journal.pgen.1010599.
2013 Lees, G.E. :
Kidney diseases caused by glomerular basement membrane type IV collagen defects in dogs. J Vet Emerg Crit Care (San Antonio) 23:184-93, 2013. Pubmed reference: 23464675. DOI: 10.1111/vec.12031.
2007 Wakamatsu, N., Surdyk, K., Carmichael, K.P., Brown, C.A. :
Histologic and ultrastructural studies of juvenile onset renal disease in four Rottweiler dogs. Vet Pathol 44:96-100, 2007. Pubmed reference: 17197631. DOI: 10.1354/vp.44-1-96.
2004 McKay, LW., Seguin, MA., Ritchey, JW., Levy, JK. :
Juvenile nephropathy in two related Pembroke Welsh corgi puppies. J Small Anim Pract 45:568-71, 2004. Pubmed reference: 15553196.
2002 Kashtan, C.E. :
Animal models of Alport syndrome. Nephrol Dial Transplant 17:1359-62, 2002. Pubmed reference: 12147777. DOI: 10.1093/ndt/17.8.1359.
2000 Peeters, D., Clercx, C., Michiels, L., Desmecht, D., Snaps, F., Henroteaux, M., Day, M.J. :
Juvenile nephropathy in a Boxer, a Rottweiler, a Collie and an Irish Wolfhound Australian Veterinary Journal 78:162-165, 2000. Pubmed reference: 10860153.
1997 Dixon, C.E. :
Juvenile nephropathy in a Dalmatian Veterinary Record 140:184, 1997. Pubmed reference: 9055399.
Knowles, J. :
Juvenile nephropathy in a Dalmatian Veterinary Record 140:240, 1997. Pubmed reference: 9076926.
Lyons, R.D., Hill, J.M., Fleming, L. :
Juvenile nephropathy in a dalmatian Veterinary Record 140:264, 1997. Pubmed reference: 9080650.
Roels, S., Schoofs, S., Ducatelle, R. :
Juvenile nephropathy in a Weimaraner dog Journal of Small Animal Practice 38:115-118, 1997. Pubmed reference: 9097243.
1994 Minkus, G., Breuer, W., Wanke, R., Reusch, C., Leuterer, G., Brem, G., Hermanns, W. :
Familial nephropathy in Bernese Mountain Dogs Veterinary Pathology 31:421-428, 1994. Pubmed reference: 7941230.
1990 Hoppe, A., Swenson, L., Jonsson, L., Hedhammar, A. :
Progressive nephropathy due to renal dysplasia in Shih-Tzu dogs in Sweden - A clinical pathological and genetic study. Journal of Small Animal Practice 31:83-91, 1990.
1987 Picut, C.A., Lewis, R.M. :
Comparative pathology of canine hereditary nephropathies: an interpretative review Veterinary Research Communications 11:561-581, 1987. Pubmed reference: 3330354.

Edit History

  • Created by Frank Nicholas on 04 Sep 2010
  • Changed by Frank Nicholas on 12 Dec 2011
  • Changed by Frank Nicholas on 17 May 2013
  • Changed by Frank Nicholas on 04 Aug 2020
  • Changed by Imke Tammen2 on 01 Feb 2023
  • Changed by Imke Tammen2 on 25 Mar 2023