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OMIA:000868-9615 : Retinal dysplasia in Canis lupus familiaris (dog)

Categories: Vision / eye phene

Single-gene trait/disorder: unknown

Disease-related: yes

Mapping: Gábor et al. (2025): "A genome-wide case–control association study of 36 adult [Czechoslovakian Wolfdogs] dogs identified association on chromosome CFA37"

Breeds: American Cocker Spaniel (Dog) (VBO_0200038), Berger Picard (Dog) (VBO_0200158), Black and Tan Coonhound (Dog) (VBO_0200168), Cavalier King Charles Spaniel (Dog) (VBO_0200309), Clumber Spaniel (Dog) (VBO_0200366), Cocker Spaniel (Dog) (VBO_0200372), Collie (Dog) (VBO_0200375), Czechoslovakian Wolfdog (Dog) (VBO_0200402), English Springer Spaniel (Dog) (VBO_0200497), Field Spaniel (Dog) (VBO_0200519), German Spitz (Dog) (VBO_0200585), Golden Retriever (Dog) (VBO_0200610), Mastiff (Dog) (VBO_0200867), Sussex Spaniel (Dog) (VBO_0201309), Yorkshire Terrier (Dog) (VBO_0201448).
Breeds in which the phene or likely causal variants have been documented. If a likely causal variant has been documented, see variant-specific breed information in the variant table. (Breed information may be incomplete).

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Cite this entry

Nicholas, F. W., Tammen, I., & Sydney Informatics Hub. (2025). OMIA:000868-9615: Online Mendelian Inheritance in Animals (OMIA) [dataset]. https://omia.org/. https://doi.org/10.25910/2AMR-PV70

References

Note: the references are listed in reverse chronological order (from the most recent year to the earliest year), and alphabetically by first author within a year.

2025 Gábor, M., Candrák, J., Miluchová, M., Zubrický, P., Balická, A., Trbolová, A. :
Initial genome-wide case-control study for genetic background of retinal dysplasia in Czechoslovakian Wolfdog. Vet Sci 12:171, 2025. Pubmed reference: 40005930. DOI: 10.3390/vetsci12020171.
2021 Genetics Committee of the American College of Veterinary Opthalmologists :
The Blue Book: Ocular disorders presumed to be inherited in purebred dogs. 13th Edition https://ofa.org/wp-content/uploads/2022/10/ACVO-Blue-Book-2021.pdf , 2021.
2020 Iwabe, S., Dufour, V.L., Guzmán, J.M., Holle, D.M., Cohen, J.A., Beltran, W.A., Aguirre, G.D. :
Focal/multifocal and geographic retinal dysplasia in the dog-In vivo retinal microanatomy analyses. Vet Ophthalmol 23:292-304, 2020. Pubmed reference: 31746146. DOI: 10.1111/vop.12725.
2017 Guandalini, A., Di Girolamo, N., Corvi, R., Santillo, D., Andreani, V., Pinzo, B. :
Epidemiology of ocular disorders presumed to be inherited in three small Italian dog breeds in Italy. Vet Ophthalmol 21:524-529, 2017. Pubmed reference: 29284193. DOI: 10.1111/vop.12542.
2010 Aguirre-Hernández, J., Sargan, D.R. :
Multifocal retinal dysplasia in the German Spitz (Klein and Mittel) is not caused by mutations in BEST1. Anim Genet 41:333-4, 2010. Pubmed reference: 19968643. DOI: 10.1111/j.1365-2052.2009.02005.x.
1999 Long, S.E., Crispin, S.M. :
Inheritance of multifocal retinal dysplasia in the Golden Retriever in the UK Veterinary Record 145:702-704, 1999. Pubmed reference: 10638798.
1979 Schmidt, G.M., Ellersieck, M.R., Wheeler, C.A., Blanchard, G.L., Keller, W.F. :
Inheritance of retinal dysplasia in the English Springer Spaniel Journal of the American Veterinary Medical Association 174:1089-1090, 1979. Pubmed reference: 438039.
1978 MacMillan, A.D., Lipton, D.E. :
Heritability of multifocal retinal dysplasia in American Cocker Spaniels Journal of the American Veterinary Medical Association 172:568-572, 1978. Pubmed reference: 632194.
Stades, F.C. :
Hereditary retinal dysplasia in a family of Yorkshire Terriers Tijdschrift voor Diergeneeskunde 103:1087-1090, 1978. Pubmed reference: 705749.
1968 Donovan, R.H., MacPherson, A.M. :
The inheritance of chorioretinal dysplasia and staphyloma in the Collie Carnivore Genetics Newsletter 5:85-89, 1968.

Edit History


  • Created by Frank Nicholas on 06 Sep 2005
  • Changed by Imke Tammen2 on 20 Apr 2025