OMIA:001055-9796 : Vitiligo in Equus caballus (horse) |
In other species: chicken , Rhesus monkey , dog , domestic cat , Northern giraffe , taurine cattle , water buffalo
Categories: Integument (skin) phene
Possibly relevant human trait(s) and/or gene(s)s (MIM numbers): 193200 (trait) , 221350 (trait) , 270750 (trait) , 277465 (trait)
Links to MONDO diseases: No links.
Mendelian trait/disorder: unknown
Considered a defect: yes
Mapping: Druml et al. (2021) "performed a GWAS analysis using high-density 670 k single nucleotide polymorphism (SNP) data from 152 Lipizzan and 104 Noriker horses, which were phenotyped for vitiligo-like depigmentation by visual inspection. ... We identified seven candidate genes on four chromosomes (ECA1, ECA13, ECA17, ECA20) putatively involved in vitiligo pathogenesis in grey horses."
Genetic engineering:
Unknown
Have human generated variants been created, e.g. through genetic engineering and gene editing
Cite this entry
Nicholas, F. W., Tammen, I., & Sydney Informatics Hub. (2021). OMIA:001055-9796: Online Mendelian Inheritance in Animals (OMIA) [dataset]. https://omia.org/. https://doi.org/10.25910/2AMR-PV70
References
Note: the references are listed in reverse chronological order (from the most recent year to the earliest year), and alphabetically by first author within a year.
2024 | Giri, P., Desai, D., Dwivedi, M. : |
Animal models unraveling the complexity of vitiligo pathogenesis. Autoimmun Rev :S1568-9972(24)00002-8:103515, 2024. Pubmed reference: 38185189. DOI: 10.1016/j.autrev.2024.103515. | |
2021 | Druml, T., Brem, G., Velie, B., Lindgren, G., Horna, M., Ricard, A., Grilz-Seger, G. : |
Equine vitiligo-like depigmentation in grey horses is related to genes involved in immune response and tumor metastasis. BMC Vet Res 17:336, 2021. Pubmed reference: 34696794. DOI: 10.1186/s12917-021-03046-x. | |
2019 | Sánchez-Guerrero, M.J., Solé, M., Azor, P.J., Sölkner, J., Valera, M. : |
Genetic and environmental risk factors for vitiligo and melanoma in Pura Raza Español horses. Equine Vet J 51:606-611, 2019. Pubmed reference: 30624804. DOI: 10.1111/evj.13067. | |
Tham, H.L., Linder, K.E., Olivry, T. : | |
Autoimmune diseases affecting skin melanocytes in dogs, cats and horses: vitiligo and the uveodermatological syndrome: a comprehensive review. BMC Vet Res 15:251, 2019. Pubmed reference: 31324191. DOI: 10.1186/s12917-019-2003-9. | |
1986 | Naughton, G.K., Mahaffey, M., Bystryn, J.C. : |
Antibodies to surface antigens of pigmented cells in animals with vitiligo. Proc Soc Exp Biol Med 181:423-6, 1986. Pubmed reference: 3511476. DOI: 10.3181/00379727-181-42275. | |
1965 | Meijer, W.C. : |
Dermatological diagnosis in horse and cattle judging. Vet Rec 77:1046-7, 1965. Pubmed reference: 5890084. DOI: 10.1136/vr.77.36.1046. | |
1962 | Meijer, W.C.P. : |
Vitiligo in seven horses and five cattle Tijdschrift voor Diergeneeskunde 87:411-425, 1962. |
Edit History
- Created by Frank Nicholas on 06 Sep 2005
- Changed by Frank Nicholas on 25 Nov 2011
- Changed by Imke Tammen2 on 28 Aug 2021
- Changed by Imke Tammen2 on 02 Nov 2021