OMIA:001093-9615 : Hepatitis, chronic active in Canis lupus familiaris (dog)

Categories: Liver/biliary system phene

Mendelian trait/disorder: yes

Mode of inheritance: X-linked

Considered a defect: yes

Key variant known: no

Species-specific description: Chronic active hepatitis is one of the common causes of hepatic encephalopathy. In reviewing the published literature on dogs, Rothuizen et al. (1993) concluded that chronic active hepatitis is a "sex-linked disorder of females", most likely due to an immune defect.

Cite this entry

Nicholas, F. W., Tammen, I., & Sydney Informatics Hub. (2012). OMIA:001093-9615: Online Mendelian Inheritance in Animals (OMIA) [dataset].


Note: the references are listed in reverse chronological order (from the most recent year to the earliest year), and alphabetically by first author within a year.

2012 Bexfield, N.H., Watson, P.J., Aguirre-Hernandez, J., Sargan, D.R., Tiley, L., Heeney, J.L., Kennedy, L.J. :
DLA class II alleles and haplotypes are associated with risk for and protection from chronic hepatitis in the English Springer spaniel. PLoS One 7:e42584, 2012. Pubmed reference: 22870335. DOI: 10.1371/journal.pone.0042584.
1995 Dillmacky, E. :
Chronic hepatitis in dogs Veterinary Clinics of North America - Small Animal Practice 25:387-398, 1995.
1993 Rothuizen, J., Cornelius, C.E. :
Portosystemic hepatic encephalopathy related with congenital and acquired hepatopathies in the dog Advances in Veterinary Science and Comparative Medicine 37:403-416, 1993. Pubmed reference: 8273522.
1988 Ingh, T.S.G.A.M. van der, Rothuizen, J., Cupery, R. :
Chronic active hepatitis with cirrhosis in the Doberman Pincher Veterinary Quarterly 10:84-89, 1988. Pubmed reference: 3413974.
1985 Crawford, M.A., Schall, W.D., Jensen, R.K., Tasker, J.B. :
Chronic active hepatitis in 26 Doberman Pinchers Journal of the American Veterinary Medical Association 187:1343-1350, 1985. Pubmed reference: 4086350.
1982 Johnson, G.F., Zawie, D.A., Gilbertson, S.R., Sternlieb, I. :
Chronic active hepatitis in Doberman Pinchers Journal of the American Veterinary Medical Association 180:1438-1442, 1982. Pubmed reference: 7096184.

Edit History

  • Created by Frank Nicholas on 06 Sep 2005
  • Changed by Frank Nicholas on 21 May 2012