OMIA:001465-9823 : Arthrogryposis multiplex congenita, generic in Sus scrofa (pig)

In other species: taurine cattle , sheep

Categories: Skeleton phene (incl. short stature & teeth)

Links to MONDO diseases: No links.

Mendelian trait/disorder: yes

Mode of inheritance: Autosomal recessive

Considered a defect: yes

Key variant known: no

Cross-species summary: conditions involving multiple joint contractures (or stiffness)

Species-specific description: Can be caused by various non-genetic factors such as ingestion of Jimsonweed or tobacco by pregnant sows. However, there is convincing evidence of a single-locus autosomal recessive form of this disorder (Lomo, 1985).

Genetic engineering: Unknown
Have human generated variants been created, e.g. through genetic engineering and gene editing

Cite this entry

Nicholas, F. W., Tammen, I., & Sydney Informatics Hub. (2020). OMIA:001465-9823: Online Mendelian Inheritance in Animals (OMIA) [dataset].


Note: the references are listed in reverse chronological order (from the most recent year to the earliest year), and alphabetically by first author within a year.

1986 Hajkova, J., Cerny, M., Borkovec, L., Lojda, L. :
[Screening for genetic health and the intensification of production of pig meat] Veterinarstvi 36:348-351, 1986.
1979 Ely, R., Leipold, H.W. :
Arthrogryposis in Yorkshire piglets Zeitschrift fur Tierzuchtung und Zuchtungsbiologie 96:241-252, 1979.
1974 Swatland, H.J. :
Developmental disorders of skeletal muscle in cattle, pigs and sheep Veterinary Bulletin 44:179-200, 1974.
1973 Crowe, M.W., Pike, H.T. :
Congenital arthrogryposis associated with ingestion of tobacco stalks by pregnant sows Journal of the American Veterinary Medical Association 162:453-455, 1973. Pubmed reference: 4692297.
Leipold, H.W., Oehme, F.W., Cook, J.E. :
Congenital arthrogryposis associated with ingestion of Jimsonweed by pregnant sows Journal of the American Veterinary Medical Association 162:1059-1060, 1973. Pubmed reference: 4709616.
1933 Hallqvist, C. :
Ein Fall von letalfaktoren beim Schwein Hereditas 18:215-224, 1933.

Edit History

  • Created by Frank Nicholas on 18 Dec 2012
  • Changed by Frank Nicholas on 16 Jan 2013
  • Changed by Frank Nicholas on 24 Jul 2020