OMIA:001598-9940 : Wool/hair shedding in Ovis aries (sheep)

In other species: taurine cattle , indicine cattle (zebu)

Categories: Integument (skin) phene

Links to MONDO diseases: No links.

Mendelian trait/disorder: yes

Mode of inheritance: Autosomal dominant

Considered a defect: no

Key variant known: no

Cross-species summary: The coat/fleece is shed naturally on a seasonal basis.

Species-specific name: Fleece shedding

Inheritance: A segregation analysis reported by Pollott (2011) provided evidence for an autosomal dominant gene of large effect associated with natural wool shedding in a flock comprising a mixture of shedding breeds. When scored on a 5-point scale (1 = no shedding; 5 = complete shedding), shedding was reported to have a heritability of 0.54 in lambs and 0.26 across all ages. Matika et al. (2013) "found strong genetic control for wool shedding, demonstrated the possibility of a single putative dominant gene controlling this trait and identified four SNPs that may be in partial linkage disequilibrium with gene(s) controlling shedding."

Genetic engineering: Unknown
Have human generated variants been created, e.g. through genetic engineering and gene editing

Cite this entry

Nicholas, F. W., Tammen, I., & Sydney Informatics Hub. (2013). OMIA:001598-9940: Online Mendelian Inheritance in Animals (OMIA) [dataset]. https://omia.org/. https://doi.org/10.25910/2AMR-PV70

References

Note: the references are listed in reverse chronological order (from the most recent year to the earliest year), and alphabetically by first author within a year.

2013 Matika, O., Bishop, S.C., Pong-Wong, R., Riggio, V., Headon, D.J. :
Genetic factors controlling wool shedding in a composite Easycare sheep flock. Anim Genet , 2013. Pubmed reference: 23837698. DOI: 10.1111/age.12070.
2011 Pollott, G.E. :
A suggested mode of inheritance for wool shedding in sheep. J Anim Sci 89:2316-25, 2011. Pubmed reference: 21357446. DOI: 10.2527/jas.2010-3713.
1980 Meyer, W., Neurand, K., Schwarz, R. :
[Hair shedding and replacement in domestic mammals.--3. Hair shedding and replacement in sheep and goat (author's transl)]. Dtsch Tierarztl Wochenschr 87:346-53, 1980. Pubmed reference: 7006996.
1965 Ryder, M.L. :
Wool fibre shedding and seasonal variation in wool growth. Proc R Soc Med 58:806-8, 1965. Pubmed reference: 5891124.

Edit History


  • Created by Frank Nicholas on 07 Sep 2011
  • Changed by Frank Nicholas on 07 Sep 2011
  • Changed by Frank Nicholas on 12 Jul 2013