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OMIA:001682-9031 : Comb traits in Gallus gallus (chicken)

Categories: Craniofacial phene

Links to MONDO diseases: No links.

Mendelian trait/disorder: unknown

Considered a defect: no

Mapping: Bakovic et al. (2022) "combined genome-wide genotype and gene expression data (> 30k genes) with different aspects of [single] comb morphology in an advanced intercross line (F8) generated by crossing a wild type Red Junglefowl with a domestic breed of chicken (White Leghorn)." They concluded: "In total, ten QTL were found associated to various aspects of comb shape and size, while 1,184 eQTL were found associated to gene expression patterns, amongst which 98 had overlapping confidence intervals with those of QTL. Our results highlight both known genomic regions confirming previous records of a large effect QTL associated to comb size, and novel QTL associated to comb shape."

Genetic engineering: Unknown
Have human generated variants been created, e.g. through genetic engineering and gene editing

Cite this entry

Nicholas, F. W., Tammen, I., & Sydney Informatics Hub. (2022). OMIA:001682-9031: Online Mendelian Inheritance in Animals (OMIA) [dataset]. https://omia.org/. https://doi.org/10.25910/2AMR-PV70

References

Note: the references are listed in reverse chronological order (from the most recent year to the earliest year), and alphabetically by first author within a year.

2022 Bakovic, V., Höglund, A., Martin Cerezo, M.L., Henriksen, R., Wright, D. :
Genomic and gene expression associations to morphology of a sexual ornament in the chicken. G3 (Bethesda) , 2022. Pubmed reference: 35801935. DOI: 10.1093/g3journal/jkac174.
2021 Yang, Z., Zou, L., Sun, T., Xu, W., Zeng, L., Jia, Y., Jiang, J., Deng, J., Yang, X. :
Genome-wide association study using whole-genome sequencing identifies a genomic region on chromosome 6 associated with comb traits in Nandan-Yao chicken. Front Genet 12:682501, 2021. Pubmed reference: 34408769. DOI: 10.3389/fgene.2021.682501.
2019 Dong, X., Li, J., Zhang, Y., Han, D., Hua, G., Wang, J., Deng, X., Wu, C. :
Genomic analysis reveals pleiotropic alleles at EDN3 and BMP7 involved in chicken comb color and egg production. Front Genet 10:612, 2019. Pubmed reference: 31316551. DOI: 10.3389/fgene.2019.00612.
2016 Shen, M., Qu, L., Ma, M., Dou, T., Lu, J., Guo, J., Hu, Y., Yi, G., Yuan, J., Sun, C., Wang, K., Yang, N. :
Genome-wide association studies for comb traits in chickens. PLoS One 11:e0159081, 2016. Pubmed reference: 27427764. DOI: 10.1371/journal.pone.0159081.
2012 Wright, D., Rubin, C., Schutz, K., Kerje, S., Kindmark, A., Brandström, H., Andersson, L., Pizzari, T., Jensen, P. :
Onset of sexual maturity in female chickens is genetically linked to loci associated with fecundity and a sexual ornament. Reprod Domest Anim 47 Suppl 1:31-6, 2012. Pubmed reference: 22212210. DOI: 10.1111/j.1439-0531.2011.01963.x.

Edit History


  • Created by Frank Nicholas on 16 Jan 2012
  • Changed by Frank Nicholas on 15 Jul 2022