OMIA:001810-9615 : Beta blocker response in heart failure in Canis lupus familiaris (dog) |
Categories: Homeostasis / metabolism phene
Links to MONDO diseases: No links.
Mendelian trait/disorder: unknown
Considered a defect: no
Mapping: Lanfear et al. (2011) conducted a GWAS on left ventricular volume and ejection fraction after beta blocker treatment in 39 dogs with experimentally-induced heart failure, using the Illumina Canine SNP 20 SNP chip (comprising ~ 22,000 SNPs). SNPs on chromosomes CFA12 and 20 showed genome-wide significance for one of the traits.
Genetic engineering:
Unknown
Have human generated variants been created, e.g. through genetic engineering and gene editing
Cite this entry
Nicholas, F. W., Tammen, I., & Sydney Informatics Hub. (2013). OMIA:001810-9615: Online Mendelian Inheritance in Animals (OMIA) [dataset]. https://omia.org/. https://doi.org/10.25910/2AMR-PV70
Reference
| 2011 | Lanfear, D.E., Yang, J.J., Mishra, S., Sabbah, H.N. : |
| Genome-wide approach to identify novel candidate genes for beta blocker response in heart failure using an experimental model. Discov Med 11:359-66, 2011. Pubmed reference: 21524389. |
Edit History
- Created by Frank Nicholas on 22 May 2013
- Changed by Frank Nicholas on 05 Aug 2013