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OMIA:002048-9913 : Hypocalcaemia, predisposition to in Bos taurus (taurine cattle)

Categories: Homeostasis / metabolism phene

Links to possible relevant human trait(s) and/or gene(s) in OMIM: 601198 (trait) , 615361 (trait)

Single-gene trait/disorder: no

Mode of inheritance: Multifactorial

Disease-related: yes

Key variant known: no

Contact us

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Cite this entry

Nicholas, F. W., Tammen, I., & Sydney Informatics Hub. (2016). OMIA:002048-9913: Online Mendelian Inheritance in Animals (OMIA) [dataset]. https://omia.org/. https://doi.org/10.25910/2AMR-PV70

References

Note: the references are listed in reverse chronological order (from the most recent year to the earliest year), and alphabetically by first author within a year.

2026 Bai, Y., Hu, J., Liu, J., Sun, X., Xu, C., Liu, J., Jia, X., Yang, Y., Wang, L., Shao, G., Zhu, Q., Ru, C., Wang, M., Xia, C., Song, Y. :
Proteomic analysis of dairy cows with persistent subclinical hypocalcemia. Animals (Basel) 16:2378, 2026. Pubmed reference: 42589015. DOI: 10.3390/ani16152378.
Chu, M., Wang, Y., Wang, Z., Lv, S. :
Calcium homeostasis and parturient paresis in ruminants: Mechanistic insights and clinical management. Animals (Basel) 16:2597, 2026. Pubmed reference: 42652002. DOI: 10.3390/ani16162597.
Melendez, P., MacKinnon, B. :
Postpartum magnesium status as an important risk factor for delayed and persistent subclinical hypocalcaemia in grazing Holstein cattle. Animal 20:S1751-7311(26)00041-8:101794, 2026. Pubmed reference: 41865582. DOI: 10.1016/j.animal.2026.101794.
Stancheva, E., Penev, T. :
Hypocalcemia in dairy Cows: A systematic review of metabolic implications and management strategies. Life (Basel) 16:1082, 2026. Pubmed reference: 42514152. DOI: 10.3390/life16071082.
2025 Hassani, R., Ghavi Hossein-Zadeh, N. :
Metabolic disorders are genetically correlated with the production and reproductive performance of dairy cows: a meta-analysis. J Dairy Res :1-11, 2025. Pubmed reference: 41131878. DOI: 10.1017/S0022029925101052.
Križanac, A.M., Reimer, C., Heise, J., Liu, Z., Pryce, J.E., Bennewitz, J., Thaller, G., Falker-Gieske, C., Tetens, J. :
Sequence-based genome-wide association study and fine-mapping in German Holstein reveal new quantitative trait loci for health traits. J Dairy Sci 108:7310-7328, 2025. Pubmed reference: 40349760. DOI: 10.3168/jds.2025-26328.
Križanac, A.M., Reimer, C., Heise, J., Liu, Z., Pryce, J.E., Bennewitz, J., Thaller, G., Falker-Gieske, C., Tetens, J. :
A large-scale multitrait meta-analysis of 11 health and 22 conformation traits in German Holstein cows. J Dairy Sci 109:1680-1699, 2025. Pubmed reference: 41274578. DOI: 10.3168/jds.2025-27087.
2024 Lozada-Soto, E.A., Parker Gaddis, K.L., Tiezzi, F., Jiang, J., Ma, L., Toghiani, S., VanRaden, P.M., Maltecca, C. :
Inbreeding depression for producer-recorded udder, metabolic, and reproductive diseases in US dairy cattle. J Dairy Sci 107:S0022-0302(23)00827-5:3032-3046, 2024. Pubmed reference: 38056567. DOI: 10.3168/jds.2023-23909.
2023 Hernandez, L.L., McArt, J.A.A. :
Perspective: Transient postparturient hypocalcemia: a lactation-induced phenomenon of high-producing dairy cows. J Dairy Sci 106:8177-8180, 2023. Pubmed reference: 37641345. DOI: 10.3168/jds.2023-23355.
McArt, J.A.A., Oetzel, G.R. :
Considerations in the diagnosis and treatment of early lactation calcium disturbances. Vet Clin North Am Food Anim Pract 39:241-259, 2023. Pubmed reference: 37032301. DOI: 10.1016/j.cvfa.2023.02.009.
Novo, L.C., Poindexter, M.B., Rezende, F.M., Santos, J.E.P., Nelson, C.D., Hernandez, L.L., Kirkpatrick, B.W., Peñagaricano, F. :
Identification of genetic variants and individual genes associated with postpartum hypocalcemia in Holstein cows. Sci Rep 13:21900, 2023. Pubmed reference: 38082150. DOI: 10.1038/s41598-023-49496-1.
2021 Lai, E., Danner, A.L., Famula, T.R., Oberbauer, A.M. :
Pleiotropic loci associated with foot disorders and common periparturient diseases in Holstein cattle. Front Genet 12:742934, 2021. Pubmed reference: 34938311. DOI: 10.3389/fgene.2021.742934.
2020 Freebern, E., Santos, D.J.A., Fang, L., Jiang, J., Parker Gaddis, K.L., Liu, G.E., VanRaden, P.M., Maltecca, C., Cole, J.B., Ma, L. :
GWAS and fine-mapping of livability and six disease traits in Holstein cattle. BMC Genomics 21:41, 2020. Pubmed reference: 31931710. DOI: 10.1186/s12864-020-6461-z.
2016 Tsiamadis, V., Banos, G., Panousis, N., Kritsepi-Konstantinou, M., Arsenos, G., Valergakis, G.E. :
Genetic parameters of subclinical macromineral disorders and major clinical diseases in postparturient Holstein cows. J Dairy Sci 99:8901-8914, 2016. Pubmed reference: 27614830. DOI: 10.3168/jds.2015-10789.

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  • Created by Frank Nicholas on 17 Oct 2016