OMIA:002085-9615 : Retinal atrophy, progressive, Whippet in Canis lupus familiaris (dog)

Categories: Vision / eye phene

Mendelian trait/disorder: yes

Mode of inheritance: Autosomal recessive

Considered a defect: yes

Key variant known: no

Clinical features: As reported by Somma et al. (2016), "The retinal dystrophy reported here in Whippet dogs has a unique phenotype of an initial lack of ERG b-wave, development of retinal bullae then a progressive generalized retinal degeneration".

Breed: Whippet (Dog) (VBO_0201421).
Breeds in which the phene has been documented. (If a likely causal variant has been documented for the phene, see the variant table breeds in which the variant has been reported).

Cite this entry

Nicholas, F. W., Tammen, I., & Sydney Informatics Hub. (2023). OMIA:002085-9615: Online Mendelian Inheritance in Animals (OMIA) [dataset]. https://omia.org/. https://doi.org/10.25910/2AMR-PV70

References

Note: the references are listed in reverse chronological order (from the most recent year to the earliest year), and alphabetically by first author within a year.

2021 Genetics Committee of the American College of Veterinary Opthalmologists :
The Blue Book: Ocular disorders presumed to be inherited in purebred dogs. 13th Edition https://ofa.org/wp-content/uploads/2022/10/ACVO-Blue-Book-2021.pdf , 2021.
2016 Somma, A.T., Moreno, J.C., Sato, M.T., Rodrigues, B.D., Bacellar-Galdino, M., Occelli, L.M., Petersen-Jones, S.M., Montiani-Ferreira, F. :
Characterization of a novel form of progressive retinal atrophy in Whippet dogs: a clinical, electroretinographic, and breeding study. Vet Ophthalmol , 2016. Pubmed reference: 27896899. DOI: 10.1111/vop.12448.

Edit History


  • Created by Frank Nicholas on 01 Dec 2016
  • Changed by Imke Tammen2 on 17 Jun 2023