OMIA:002570-38626 : Chlamydia infection, susceptibility to in Phascolarctos cinereus (koala)

Categories: Immune system phene

Links to MONDO diseases: No links.

Mendelian trait/disorder: no

Mode of inheritance: Multifactorial

Considered a defect: yes

Key variant known: no

Inheritance: Cristescu et al. (2022) "investigated the genetic basis of variation in susceptibility to chlamydia ... . We combined data from veterinary examinations, chlamydia testing, genetic sampling and movement monitoring. Out of our sample of 342 wild koalas, 60 were found to have chlamydia. Using genotype information on 5007 SNPs to investigate the role of genetic variation in determining disease status, we found no evidence of inbreeding depression, but a heritability of 0.11 (95%CI = 0.06 - 0.23) for the probability that koalas had chlamydia."

Genetic engineering: Unknown
Have human generated variants been created, e.g. through genetic engineering and gene editing

Cite this entry

Nicholas, F. W., Tammen, I., & Sydney Informatics Hub. (2022). OMIA:002570-38626: Online Mendelian Inheritance in Animals (OMIA) [dataset].


Note: the references are listed in reverse chronological order (from the most recent year to the earliest year), and alphabetically by first author within a year.

2023 Charalambous, R., Narayan, E. :
Correction: A 29-year retrospective analysis of koala rescues in New South Wales, Australia. PLoS One 18:e0292911, 2023. Pubmed reference: 37815993. DOI: 10.1371/journal.pone.0292911.
2022 Cristescu, R.H., Strickland, K., Schultz, A.J., Kruuk, L.E.B., de Villiers, D., Frère, C.H. :
Susceptibility to a sexually transmitted disease in a wild koala population shows heritable genetic variance but no inbreeding depression. Mol Ecol , 2022. Pubmed reference: 36043238. DOI: 10.1111/mec.16676.

Edit History

  • Created by Imke Tammen2 on 11 Sep 2022