Categories: Homeostasis / metabolism phene

Links to MONDO diseases: No links.

Mendelian trait/disorder: unknown

Considered a defect: no

Species-specific description: Coogan et al. (2023) used CRISPR/Cas9 technology to 'knock in' a masu salmon elongase gene into the channel catfish melanocortin-4 receptor (mc4r) gene site: "To our knowledge this is the first example of genome engineering to simultaneously target transgenesis and knock-out a gene in a commercially important aquaculture species for multiple improved performance traits. With a high transgene integration rate, improved growth, and higher omega-3 fatty acid content, the use of ... transgenic channel catfish appears beneficial for application on commercial farms." (GMO)

Genetic engineering: Yes - variants have been created artificially, e.g. by genetic engineering or gene editing
Have human generated variants been created, e.g. through genetic engineering and gene editing