OMIA:002919-9615 : Carcinoma, gastric, susceptibility to in Canis lupus familiaris (dog)

Categories: Neoplasm

Single-gene trait/disorder: no

Mode of inheritance: Multifactorial

Disease-related: yes

Key variant known: no

Inheritance: Hugen et al. (2025)  estimated the heritability of gastric carcinoma (GC) in Tervueren and Groenendael Belgian Shepherds: "The heritability of GC in the narrow sense was calculated as 0.53 with a standard error of 0.15."

Breeds: Belgian Shepherd Dog, Groenendael (Dog) (VBO_0200145), Belgian Shepherd Dog, Tervueren (Dog) (VBO_0200148), Chow Chow (Dog) (VBO_0200361).
Breeds in which the phene or likely causal variants have been documented. If a likely causal variant has been documented, see variant-specific breed information in the variant table. (Breed information may be incomplete).

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Cite this entry

Nicholas, F. W., Tammen, I., & Sydney Informatics Hub. (2025). OMIA:002919-9615: Online Mendelian Inheritance in Animals (OMIA) [dataset]. https://omia.org/. https://doi.org/10.25910/2AMR-PV70

References

Note: the references are listed in reverse chronological order (from the most recent year to the earliest year), and alphabetically by first author within a year.

2025 Hugen, S., Limpens, C., Robben, J.H., Fieten, H., Mandigers, P.J.J. :
Incidence and heritability of gastric carcinoma in the Belgian Shepherd dog population in the Netherlands. Vet Sci 12:18, 2025. Pubmed reference: 39852893. DOI: 10.3390/vetsci12010018.
2023 Kijan, C., Hugen, S., Thomas, R.E., Oberbauer, A.M., Leegwater, P.A.J., Fieten, H., German, A.J., Mandigers, P.J.J. :
The histopathological characteristic of gastric carcinoma in the Belgian Tervueren and Groenendael dog: A comparison of two classification methods. Animals (Basel) 13:1532, 2023. Pubmed reference: 37174569. DOI: 10.3390/ani13091532.
2022 Candido, M.V., Syrjä, P., Kilpinen, S., Meisner, S., Hanifeh, M., Spillmann, T. :
Can chromoendoscopy improve the early diagnosis of gastric carcinoma in dogs? Animals (Basel) 12:2253, 2022. Pubmed reference: 36077972. DOI: 10.3390/ani12172253.
2021 Cândido, M.V., Syrjä, P., Hanifeh, M., Lepajõe, J., Salla, K., Kilpinen, S., Noble, P.M., Spillmann, T. :
Gastric mucosal pathology in Belgian Shepherd dogs with and without clinical signs of gastric disease. Acta Vet Scand 63:7, 2021. Pubmed reference: 33563310. DOI: 10.1186/s13028-021-00570-6.
2020 Koterbay, A.M., Muthupalani, S., Fox, J.G., McNiel, E.A. :
Risk and characteristics of gastric carcinoma in the chow chow dog. Can Vet J 61:396-400, 2020. Pubmed reference: 32255825.
2019 Seim-Wikse, T., Skancke, E., Nødtvedt, A., Jörundsson, E., Grotmol, T., Kristensen, A.T., Bjørnvad, C.R. :
Comparison of body condition score and other minimally invasive biomarkers between dogs with gastric carcinoma and dogs with chronic gastritis. J Am Vet Med Assoc 254:226-235, 2019. Pubmed reference: 30605380. DOI: 10.2460/javma.254.2.226.
2013 Seim-Wikse, T., Jörundsson, E., Nødtvedt, A., Grotmol, T., Bjornvad, C.R., Kristensen, A.T., Skancke, E. :
Breed predisposition to canine gastric carcinoma--a study based on the Norwegian canine cancer register. Acta Vet Scand 55:25, 2013. Pubmed reference: 23514604. DOI: 10.1186/1751-0147-55-25.
2009 Lubbes, D., Mandigers, P.J., Heuven, H.C., Teske, E. :
[Incidence of gastric carcinoma in Dutch Tervueren shepherd dogs born between 1991 and 2002]. Tijdschr Diergeneeskd 134:606-10, 2009. Pubmed reference: 19697677.
2002 Swann, H.M., Holt, D.E. :
Canine gastric adenocarcinoma and leiomyosarcoma: a retrospective study of 21 cases (1986-1999) and literature review. J Am Anim Hosp Assoc 38:157-64, 2002. Pubmed reference: 11908834. DOI: 10.5326/0380157.
1987 Sullivan, M., Lee, R., Fisher, E.W., Nash, A.S., McCandlish, I.A. :
A study of 31 cases of gastric carcinoma in dogs. Vet Rec 120:79-83, 1987. Pubmed reference: 3029939. DOI: 10.1136/vr.120.4.79.

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  • Created by Imke Tammen2 on 29 Jan 2025
  • Changed by Imke Tammen2 on 29 Jan 2025