Categories: Skeleton phene (incl. short stature & teeth)

Links to possible relevant human trait(s) and/or gene(s) in OMIM: 112266 (gene)

Single-gene trait/disorder: yes

Disease-related: yes

Key variant known: no

Species summary: Li et al. (2024) used CRISPR/Cas9 technology to disrupt the bmp6 gene in silver carp. The created chimeric fish "exhibited complete viability, normal appearance, and partial intermuscular bones loss, with approximately 30% of them displaying rib bifurcation or bending." This phene includes references to studies involving gene edited or genetically modified organisms (GMO).

Genetic engineering: Yes - variants have been created artificially, e.g. by genetic engineering or gene editing
Have human generated variants been created, e.g. through genetic engineering and gene editing

Associated gene: