OMIA:003030-35732 : Anticoagulant rodenticide resistance, VKORC1-related in Rattus tanezumi (Oriental house rat) |
Categories: Haematopoietic system phene , Homeostasis / metabolism phene
Links to possible relevant human trait(s) and/or gene(s) in OMIM: 122700 (trait) , 608547 (gene)
Single-gene trait/disorder: yes
Mode of inheritance: Autosomal dominant
Disease-related: no
Key variant known: no
Markers: Sun et al. (2025) "sequenced the mitochondrial Cyt b, D-loop and Vkorc1 genes in different R. tanezumi populations [and] ... identiļ¬ed two resistance-conferring Vkorc1 mutations (Y139C and A26T) occurring on four distinct haplotypes, indicating multiple independent evolutionary origins of resistance."
Associated gene:
| Symbol | Description | Species | Chr | Location | OMIA gene details page | Other Links |
|---|---|---|---|---|---|---|
| Vkorc1 | Rattus tanezumi | - | no genomic information (-..-) | Vkorc1 | Ensembl |
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Cite this entry
Nicholas, F. W., Tammen, I., & Sydney Informatics Hub. (2026). OMIA:003030-35732: Online Mendelian Inheritance in Animals (OMIA) [dataset]. https://omia.org/. https://doi.org/10.25910/2AMR-PV70
Reference
| 2025 | Sun, T., Chen, Y., Li, N., Liu, X.H., Wang, D., Jing, M., Yang, X., Song, Y. : |
| Rapid population expansion drives the widespread spread of a dominant anticoagulant-resistance Vkorc1 allele in Asian house rats (Rattus tanezumi) across China. Pest Manag Sci , 2025. Pubmed reference: 41436863. DOI: 10.1002/ps.70480. |
Edit History
- Created by Imke Tammen2 on 05 Jan 2026
- Changed by Imke Tammen2 on 05 Jan 2026