Gene F8 : coagulation factor VIII, procoagulant component in Sus scrofa

See the equivalent entry at NCBI

In other species: dog , taurine cattle , sheep

Symbol: F8

Description: coagulation factor VIII, procoagulant component

Type of gene: protein-coding

NCBI gene id: 397339

Other designations: coagulation factor VIII|coagulation factor VIII, procoagulant component (hemophilia A)|factor VIII|procoagulant component

Links: Homologene , Ensembl

Genomic location: X:125350853..125265330 [Chromosome accession NC_010461.5]


Note: the references are listed in reverse chronological order (from the most recent year to the earliest year), and alphabetically by first author within a year.
2015 Lillicrap, D., Schiviz, A., Apostol, C., Wojciechowski, P., Horling, F., Lai, C.K., Piskernik, C., Hoellriegl, W., Lollar, P. :
Porcine recombinant factor VIII (Obizur; OBI-1; BAX801): product characteristics and preclinical profile. Haemophilia , 2015. Pubmed reference: 26278557. DOI: 10.1111/hae.12784.
Mannucci, P.M. :
Recombinant porcine factor VIII: a new installment of a long story. Haemophilia 21:149-51, 2015. Pubmed reference: 25655769. DOI: 10.1111/hae.12612.
2012 Giangrande, P.L. :
Porcine factor VIII. Haemophilia 18:305-9, 2012. Pubmed reference: 22531020. DOI: 10.1111/j.1365-2516.2012.02803.x.
Kashiwakura, Y., Mimuro, J., Onishi, A., Iwamoto, M., Madoiwa, S., Fuchimoto, D., Suzuki, S., Suzuki, M., Sembon, S., Ishiwata, A., Yasumoto, A., Sakata, A., Ohmori, T., Hashimoto, M., Yazaki, S., Sakata, Y. :
Porcine model of hemophilia a. PLoS One 7:e49450, 2012. Pubmed reference: 23209578. DOI: 10.1371/journal.pone.0049450.
Kempton, C.L., Abshire, T.C., Deveras, R.A., Hoots, W.K., Gill, J.C., Kessler, C.M., Key, N.S., Konkle, B.A., Kuriakose, P., Macfarlane, D.E., Bergman, G. :
Pharmacokinetics and safety of OBI-1, a recombinant B domain-deleted porcine factor VIII, in subjects with haemophilia A. Haemophilia 18:798-804, 2012. Pubmed reference: 22512291. DOI: 10.1111/j.1365-2516.2012.02789.x.
2010 Toschi, V. :
OBI-1, porcine recombinant Factor VIII for the potential treatment of patients with congenital hemophilia A and alloantibodies against human Factor VIII. Curr Opin Mol Ther 12:617-25, 2010. Pubmed reference: 20886394.
2006 Barrow, R.T., Lollar, P. :
Neutralization of antifactor VIII inhibitors by recombinant porcine factor VIII. J Thromb Haemost 4:2223-9, 2006. Pubmed reference: 16856973. DOI: 10.1111/j.1538-7836.2006.02135.x.
1991 Morrison, A.E., Ludlam, C.A. :
The use of porcine factor VIII in the treatment of patients with acquired hemophilia: the United Kingdom experience. Am J Med 91:23S-26S, 1991. Pubmed reference: 1746592.