OMIA:000259-9685 : Deafness, generic in Felis catus (domestic cat)

In other species: dog , horse , pig , llama , alpaca , American mink

Categories: Hearing / vestibular / ear phene

Mendelian trait/disorder: unknown

Considered a defect: yes

Cite this entry

Nicholas, F. W., Tammen, I., & Sydney Informatics Hub. (2022). OMIA:000259-9685: Online Mendelian Inheritance in Animals (OMIA) [dataset].


Note: the references are listed in reverse chronological order (from the most recent year to the earliest year), and alphabetically by first author within a year.

2024 Kortas, A., Pomianowski, A., Kolecka, M., Rytel, L. :
Sensorineural deafness in purebred white Devon Rex cats. J Vet Intern Med 38:1120-1126, 2024. Pubmed reference: 38332646. DOI: 10.1111/jvim.17007.
2023 Awazu, A., Takemoto, D., Watanabe, K., Sakamoto, N. :
Possibilities of skin coat color-dependent risks and risk factors of squamous cell carcinoma and deafness of domestic cats inferred via RNA-seq data. Genes Cells 28:893-905, 2023. Pubmed reference: 37864512. DOI: 10.1111/gtc.13076.
2022 Annemarie, K., Liliana, R., MaƂgorzata, K., Andrzej, P. :
Evaluation of the prevalence of congenital sensorineural deafness in a population of 72 client-owned purebred white cats examined from 2007 to 2021. BMC Vet Res 18:287, 2022. Pubmed reference: 35869465. DOI: 10.1186/s12917-022-03378-2.
2017 Strain, G.M. :
Hearing disorders in cats. J Feline Med Surg 19:276-287, 2017. Pubmed reference: 28245737. DOI: 10.1177/1098612X17695062.
2016 Land, R., Baumhoff, P., Tillein, J., Lomber, S.G., Hubka, P., Kral, A. :
Cross-Modal Plasticity in Higher-Order Auditory Cortex of Congenitally Deaf Cats Does Not Limit Auditory Responsiveness to Cochlear Implants. J Neurosci 36:6175-85, 2016. Pubmed reference: 27277796. DOI: 10.1523/JNEUROSCI.0046-16.2016.
2015 Strain, G.M. :
The genetics of deafness in domestic animals. Front Vet Sci 2:29, 2015. Pubmed reference: 26664958. DOI: 10.3389/fvets.2015.00029.
2012 Ryugo, D.K., Menotti-Raymond, M. :
Feline deafness. Vet Clin North Am Small Anim Pract 42:1179-207, 2012. Pubmed reference: 23122176. DOI: 10.1016/j.cvsm.2012.08.008.
2009 Cvejic, D., Steinberg, TA., Kent, MS., Fischer, A. :
Unilateral and bilateral congenital sensorineural deafness in client-owned pure-breed white cats. J Vet Intern Med 23:392-5, 2009. Pubmed reference: 19192155. DOI: 10.1111/j.1939-1676.2008.0262.x.
2007 Geigy, CA., Heid, S., Steffen, F., Danielson, K., Jaggy, A., Gaillard, C. :
Does a pleiotropic gene explain deafness and blue irises in white cats? Vet J 173:548-53, 2007. Pubmed reference: 16956778. DOI: 10.1016/j.tvjl.2006.07.021.
Strain, G.M. :
Deafness in blue eyed white cats: the uphill road to solving polygenic disorders. Vet J 173:471-2, 2007. Pubmed reference: 17317244. DOI: 10.1016/j.tvjl.2006.01.015.
2003 Ryugo, DK., Cahill, HB., Rose, LS., Rosenbaum, BT., Schroeder, ME., Wright, AL. :
Separate forms of pathology in the cochlea of congenitally deaf white cats. Hear Res 181:73-84, 2003. Pubmed reference: 12855365.
2002 Redd, E.E., Cahill, H.B., Pongstaporn, T., Ryugo, D.K. :
The effects of congenital deafness on auditory nerve synapses: Type I and type II multipolar cells in the anteroventral cochlear nucleus of cats J Assoc Res Otolaryngol 3:403-417, 2002. Pubmed reference: 12486596. DOI: 10.1007/s101620020043.
1999 Strain, G.M. :
Congenital deafness and its recognition Veterinary Clinics of North America - Small Animal Practice 29:895-+, 1999.
1998 Heid, S., Hartmann, R., Klinke, R. :
A model for prelingual deafness, the congenitally deaf white cat - population statistics and degenerative changes Hearing Research 115:101-112, 1998. Pubmed reference: 9472739.
Ryugo, D.K., Rosenbaum, B.T., Kim, P.J., Niparko, J.K., Saada, A.A. :
Single unit recordings in the auditory nerve of congenitally deaf white cats - morphological correlates in the cochlea and cochlear nucleus Journal of Comparative Neurology 397:532-548, 1998. Pubmed reference: 9699914.
Steffen, F., Jaggy, A. :
Deafness and its diagnosis in dogs and cats [German] Schweizer Archiv fur Tierheilkunde 140:397-404, 1998. Pubmed reference: 9803159.
1997 Hartmann, R., Shepherd, R.K., Heid, S., Klinke, R. :
Response of the primary auditory cortex to electrical stimulation of the auditory nerve in the congenitally deaf white cat Hearing Research 112:115-133, 1997. Pubmed reference: 9367234.
Huchton, D.M., Pongstaporn, T., Niparko, J.K., Ryugo, D.K. :
Ultrastructural changes in primary endings of deaf white cats Otolaryngology & Head & Neck Surgery 116:286-293, 1997.
Ryugo, D.K., Pongstaporn, T., Huchton, D.M., Niparko, J.K. :
Ultrastructural analysis of primary endings in deaf white cats - morphologic alterations in endbulbs of held Journal of Comparative Neurology 385:230-244, 1997. Pubmed reference: 9268125.
1996 Saada, A.A., Niparko, J.K., Ryugo, D.K. :
Morphological changes in the cochlear nucleus of congenitally deaf white cats Brain Research 736:315-328, 1996. Pubmed reference: 8930338.
Strain, G.M. :
Aetiology, prevalence and diagnosis of deafness in dogs and cats [Review] Br Vet J 152:17-36, 1996. Pubmed reference: 8634862. DOI: 10.1016/s0007-1935(96)80083-2.
1995 Wegner, W. :
The Applicability of Animal Protection Law for the Prevention of Crippling Breeding Methods Praktische Tierarzt 76:11, 1995.
1991 Strain, G.M. :
Congenital Deafness in Dogs and Cats Compendium on Continuing Education for the Practicing Veterinarian 13:245, 1991.
1973 Mair, IW. :
Hereditary deafness in the white cat. Acta Otolaryngol Suppl 314:1-48, 1973. Pubmed reference: 4363431.
West, C.D., Harrison, J.M. :
Transneuronal cell atrophy in the congenitally deaf white cat Journal of Comparative Neurology 151:377-398, 1973. Pubmed reference: 4754840. DOI: 10.1002/cne.901510406.
1971 Bergsma, D.R., Brown, K.S. :
White fur, blue eyes and deafness in the domestic cat Journal of Heredity 62:171-185, 1971. Pubmed reference: 5137350.
1965 Bosher, S.K., Hallpike, C.S. :
Observations of the histological features, development and pathogenesis of the inner ear degeneration of the deaf white cat Proceedings of the Royal Society. Series B 162:147-170, 1965.
1959 Robinson, R. :
Genetics of the domestic cat Bibliographia Genetica 18:273-362, 1959.
Wilson, T.G., Kane, F. :
Congenital deafness in white cats Acta Oto-Laryngologica 50:269-277, 1959. Pubmed reference: 13660786.
1942 Wolff, D. :
Three generations of deaf white cats Journal of Heredity 33:39-43, 1942.
1918 Wright, S. :
Color inheritance in mammals. X. The cat - Curious association of deafness with blue-eyed white color and femaleness with tortoise-shelled color, long known - variations of tiger pattern present in interesting features Journal of Heredity 9:139-144, 1918. DOI: 10.1093/oxfordjournals.jhered.a111923.
1884 Bell, A.G. :
Deafness in white cats. Science 3:171, 1884. Pubmed reference: 17738188. DOI: 10.1126/science.ns-3.54.171.
Bell, A.G. :
Deafness in white cats, and statistics of deafness and epilepsy in America. Science 3:243-4, 1884. Pubmed reference: 17808809. DOI: 10.1126/science.ns-3.56.243-a.
1883 Tait, L. :
Notes on deafness in white cats. Nature 29:164 only, 1883. DOI: 10.1038/029164a0.
1873 Tait, L. :
Note on a polydactylous cat from Cookham-Dean. Nature 7:323 only, 1873. DOI: 10.1038/007323b0.

Edit History

  • Created by Frank Nicholas on 06 Sep 2005
  • Changed by Imke Tammen2 on 12 Sep 2022