OMIA:000337-9615 : Entropion in Canis lupus familiaris (dog)

In other species: domestic cat , horse , pig , taurine cattle , goat , sheep , rabbit

Categories: Vision / eye phene

Mendelian trait/disorder: unknown

Considered a defect: yes

Cross-species summary: Inversion (turning inward) of the margin of the eyelid.

Species-specific description: Genetics Committee of the American College of Veterinary Opthalmologists (2021): Entropion is "a conformational defect resulting in inversion of the eyelid margin which may cause ocular irritation. It is likely that entropion is influenced by several factors defining the skin and other structures, which make up the eyelids, orbital contents, and conformation of the skull."

Breeds: Anatolian Shepherd Dog (Dog) (VBO_0200062), Chinese Shar-Pei (Dog) (VBO_0200351), Pug (Dog) (VBO_0201089), Shih Tzu (Dog) (VBO_0201223).
Breeds in which the phene has been documented. (If a likely causal variant has been documented for the phene, see the variant table breeds in which the variant has been reported).

Cite this entry

Nicholas, F. W., Tammen, I., & Sydney Informatics Hub. (2024). OMIA:000337-9615: Online Mendelian Inheritance in Animals (OMIA) [dataset].


Note: the references are listed in reverse chronological order (from the most recent year to the earliest year), and alphabetically by first author within a year.

2024 [No authors listed] :
Entropion - the most common condition in shar pei dogs. Vet Rec 194:7, 2024. Pubmed reference: 38180193. DOI: 10.1002/vetr.3803.
Rajaei, S.M., Faghihi, H., Zahirinia, F. :
The Shih Tzu eye: Ophthalmic findings of 1000 eyes. Vet Ophthalmol , 2024. Pubmed reference: 38169085. DOI: 10.1111/vop.13182.
2023 O'Neill, D.G., Engdahl, K.S., Leach, A., Packer, R.M.A., Church, D.B., Brodbelt, D.C. :
Is it now time to iron out the wrinkles? Health of Shar Pei dogs under primary veterinary care in the UK. Canine Med Genet 10:11, 2023. Pubmed reference: 38093396. DOI: 10.1186/s40575-023-00134-z.
Saito, A., Iwashita, H. :
Novel findings on the anatomy of medial canthus in dogs. Vet Ophthalmol 26:315-323, 2023. Pubmed reference: 36847328. DOI: 10.1111/vop.13072.
Walter, H., Bilotta, T., Goncalves, C., Busse, C. :
A combination of modified Kuhnt-Szymanowski and Celsus-Hotz techniques for correction of entropion and overlong lower eyelids in dogs (40 eyes). Vet Ophthalmol , 2023. Pubmed reference: 36948518. DOI: 10.1111/vop.13084.
2021 Costa, J., Steinmetz, A., Delgado, E. :
Clinical signs of brachycephalic ocular syndrome in 93 dogs. Ir Vet J 74:3, 2021. Pubmed reference: 33494828. DOI: 10.1186/s13620-021-00183-5.
Genetics Committee of the American College of Veterinary Opthalmologists :
The Blue Book: Ocular disorders presumed to be inherited in purebred dogs. 13th Edition , 2021.
2019 McDonald, J.E., Knollinger, A.M. :
The use of hyaluronic acid subdermal filler for entropion in canines and felines: 40 cases. Vet Ophthalmol 22:105-115, 2019. Pubmed reference: 29520917. DOI: 10.1111/vop.12566.
2017 Guandalini, A., Di Girolamo, N., Corvi, R., Santillo, D., Andreani, V., Pinzo, B. :
Epidemiology of ocular disorders presumed to be inherited in three small Italian dog breeds in Italy. Vet Ophthalmol 21:524-529, 2017. Pubmed reference: 29284193. DOI: 10.1111/vop.12542.
2016 Guandalini, A., Di Girolamo, N., Santillo, D., Andreani, V., Corvi, R., Bandini, M., Peruccio, C. :
Epidemiology of ocular disorders presumed to be inherited in three large Italian dog breeds in Italy. Vet Ophthalmol 20:420-426, 2016. Pubmed reference: 27860098. DOI: 10.1111/vop.12442.
2015 Krecny, M., Tichy, A., Rushton, J., Nell, B. :
A retrospective survey of ocular abnormalities in pugs: 130 cases. J Small Anim Pract 56:96-102, 2015. Pubmed reference: 25370448. DOI: 10.1111/jsap.12291.
2007 Read, R.A., Broun, H.C. :
Entropion correction in dogs and cats using a combination Hotz-Celsus and lateral eyelid wedge resection: results in 311 eyes. Vet Ophthalmol 10:6-11, 2007. Pubmed reference: 17204122. DOI: 10.1111/j.1463-5224.2007.00482.x.
1999 Willis, A.M., Martin, C.L., Stiles, J., Kirschner, S.E. :
Brow suspension for treatment of ptosis and entropion in dogs with redundant facial skin folds Journal of the American Veterinary Medical Association 214:660-+, 1999. Pubmed reference: 10088013.
1995 Schoofs, S. :
Ectropion and entropion in the Shar Pei [Dutch] Vlaams Diergeneeskundig Tijdschrift 64:156, 1995.
1990 Gorgul, O.S., Intas, D.S. :
Bilateral congenital entropion in a female Karabas dog. Praktische Tierarzt 71:22-23, 1990.

Edit History

  • Created by Frank Nicholas on 06 Sep 2005
  • Changed by Imke Tammen2 on 17 Jun 2023
  • Changed by Imke Tammen2 on 08 Jan 2024
  • Changed by Imke Tammen2 on 09 Jan 2024