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OMIA 000214-9685 : Coat colour, white spotting in Felis catus

In other species: dog , horse , llama , cattle , domestic guinea pig , water buffalo

Possibly relevant human trait(s) and/or gene(s)s (MIM numbers): 193510 (trait) , 103500 (trait) , 156845 (gene)

Mendelian trait/disorder: yes

Mode of inheritance: Autosomal Co-Dominant

Considered a defect: no

Key variant known: no

Cross-species summary: Variable degree of white spotting ranging from tiny white spots up to completely white animals. The absence of pigment is caused by the absence of skin melanocytes ("leucism"), not by failure in the biochemical reactions required for pigment synthesis.

References


Note: the references are listed in reverse chronological order (from the most recent year to the earliest year), and alphabetically by first author within a year.
2000 Christensen, A.C. :
Cats as an aid to teaching genetics. Genetics 155:999-1004, 2000. Pubmed reference: 10880464.
1987 Wagner, A., Wolsan, M. :
Pelage mutant allele frequencies in domestic cat populations of Poland. J Hered 78:197-200, 1987. Pubmed reference: 3611716.
1977 Davis, BK., Davis, BP. :
Allele frequencies in a cat population in Budapest. J Hered 68:31-4, 1977. Pubmed reference: 864231.
1928 Kuhn, A, Kroning, F. :
Uber der Verebung der Weisezchung bei der Hauskatze Zuchtungskunde 3:448-454, 1928.
1919 Whiting, P.W. :
Inheritance of white spotting and other colour characteristics in cats American Naturalist 53:473-482, 1919.
1884 Bell, A.G. :
Deafness in white cats. Science 3:171, 1884. Pubmed reference: 17738188. DOI: 10.1126/science.ns-3.54.171.
Bell, A.G. :
Deafness in white cats, and statistics of deafness and epilepsy in America. Science 3:243-4, 1884. Pubmed reference: 17808809. DOI: 10.1126/science.ns-3.56.243-a.
1883 Tait, L. :
Notes on Deafness in White Cats Nature 29:164 only, 1883. DOI: 10.1038/029164a0.
1873 Tait, L. :
Note on a Polydactylous Cat from Cookham-Dean. Nature 7:323 only, 1873. DOI: 10.1038/007323b0 .

Edit History


  • Created by Frank Nicholas on 28 Aug 2006
  • Changed by Frank Nicholas on 29 Aug 2014
  • Changed by Frank Nicholas on 16 Apr 2015
  • Changed by Frank Nicholas on 14 Mar 2017