In other species: dog , pig , taurine cattle , sheep

Categories: Limbs / fins / digit / tail phene

Links to MONDO diseases: No links.

Mendelian trait/disorder: unknown

Considered a defect: no

Cross-species summary: Absence of the tail. Also called anury.

Molecular basis: Xia et al. (2024) "present evidence that an individual insertion of an Alu element in the genome of the hominoid ancestor may have contributed to tail-loss evolution. [The authors] demonstrate that this Alu element—inserted into an intron of the TBXT gene pairs with a neighbouring ancestral Alu element encoded in the reverse genomic orientation and leads to a hominoid-specific alternative splicing event."

Genetic engineering: Unknown
Have human generated variants been created, e.g. through genetic engineering and gene editing