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OMIA:001579-9940 : Ear size in Ovis aries (sheep)

In other species: pig , taurine cattle , woolly mammoth

Categories: Hearing / vestibular / ear phene

Possibly relevant human trait(s) and/or gene(s)s (MIM numbers): 600409 (gene) , 605186 (gene)

Links to MONDO diseases: No links.

Mendelian trait/disorder: unknown

Considered a defect: no

Mapping: Cheng et al. (2023) analysed “whole-genome sequencing individuals of 1,098 domestic sheep from 154 breeds, and 69 wild sheep from seven Ovis species. … several introgressed haplotypes contributed to the morphological differentiations across sheep breeds, … a MSRB3 haplotype from argali strongly associated with ear morphology … .”

Genetic engineering: Unknown
Have human generated variants been created, e.g. through genetic engineering and gene editing

Cite this entry

Nicholas, F. W., Tammen, I., & Sydney Informatics Hub. (2023). OMIA:001579-9940: Online Mendelian Inheritance in Animals (OMIA) [dataset]. https://omia.org/. https://doi.org/10.25910/2AMR-PV70

References

Note: the references are listed in reverse chronological order (from the most recent year to the earliest year), and alphabetically by first author within a year.

2024 Klawatsch, J., Papachristou, D., Koutsouli, P., Upadhyay, M., Seichter, D., Russ, I., Mioč, B., Simčič, M., Bizelis, I., Medugorac, I. :
Genetic basis of ear length in sheep breeds sampled across the region from the Middle East to the Alps. Anim Genet 55:123-133, 2024. Pubmed reference: 38069488. DOI: 10.1111/age.13387.
2023 Cheng, H., Zhang, Z., Wen, J., Lenstra, J.A., Heller, R., Cai, Y., Guo, Y., Li, M., Li, R., Li, W., He, S., Wang, J., Shao, J., Song, Y., Zhang, L., Billah, M., Wang, X., Liu, M., Jiang, Y. :
Long divergent haplotypes introgressed from wild sheep are associated with distinct morphological and adaptive characteristics in domestic sheep. PLoS Genet 19:e1010615, 2023. Pubmed reference: 36821549. DOI: 10.1371/journal.pgen.1010615.
2021 Salehian-Dehkordi, H., Xu, Y.X., Xu, S.S., Li, X., Luo, L.Y., Liu, Y.J., Wang, D.F., Cao, Y.H., Shen, M., Gao, L., Chen, Z.H., Glessner, J.T., Lenstra, J.A., Esmailizadeh, A., Li, M.H., Lv, F.H. :
Genome-wide detection of copy number variations and their association with distinct phenotypes in the world's sheep. Front Genet 12:670582, 2021. Pubmed reference: 34093663. DOI: 10.3389/fgene.2021.670582.
2020 Zhao, F., Deng, T., Shi, L., Wang, W., Zhang, Q., Du, L., Wang, L. :
Genomic scan for selection signature reveals fat deposition in Chinese indigenous sheep with extreme tail types. Animals (Basel) 10:773, 2020. Pubmed reference: 32365604. DOI: 10.3390/ani10050773.

Edit History


  • Created by Imke Tammen2 on 16 Jun 2021
  • Changed by Imke Tammen2 on 25 Feb 2023