OMIA:001715-9798 : Gaitedness, DMRT3-related in Equus przewalskii (Przewalski's horse)

In other species: ass (donkey) , horse , mule

Categories: Normal phene

Links to possible relevant human trait(s) and/or gene(s) in OMIM: 614754 (gene)

Mendelian trait/disorder: unknown

Considered a defect: no

Year key variant first reported: 2012

Cross-species summary: All horses have three naturally occurring gaits, namely (in order of increasing speed) walk (four-beat, lateral), trot (two-beat, diagonal) and gallop (four-beat). Some breeds of horse exhibit more than one form of a particular gait, particularly at intermediate speeds. The alternate forms of intermediate-speed gait are classified as pace (a two-beat gait) or ambling (a four-beat gait), which can be regular (including the Tölt gait of Icelandic horses), lateral or diagonal. Some breeds are four-gaited (e.g. walk, tölt, trot and gallop) and others are five-gaited (e.g. walk, tölt, trot, gallop and pace). "Gaitedness" is the ability to exhibit alternate forms of gait. Gaited breeds included Icelandic horses, Kentucky mountain saddle horse, Missouri fox trotter, Paso fino, Peruvian paso, and Rocky mountain horse, Tennessee walking horse. Non-gaited breeds include Arabian horse, Gotland pony, North-Swedish draft horse, Przewalski’s horse, Shetland pony, Swedish ardennes, Swedish warmblood, and Thoroughbred. (Information taken from Andersson et al., 2012)
Renamed from 'Gaitedness' to 'Gaitedness, DMRT3-related' [10/06/2024]

Species-specific description: See OMIA:001715-9796 : Gaitedness in Equus caballus (horse) for details.

Associated gene:

Symbol Description Species Chr Location OMIA gene details page Other Links
DMRT3 Equus przewalskii - no genomic information (-..-) DMRT3 Ensembl

Cite this entry

Nicholas, F. W., Tammen, I., & Sydney Informatics Hub. (2024). OMIA:001715-9798: Online Mendelian Inheritance in Animals (OMIA) [dataset].


Note: the references are listed in reverse chronological order (from the most recent year to the earliest year), and alphabetically by first author within a year.

2017 Staiger, E.A., Almén, M.S., Promerová, M., Brooks, S., Cothran, E.G., Imsland, F., Jäderkvist Fegraeus, K., Lindgren, G., Mehrabani Yeganeh, H., Mikko, S., Vega-Pla, J.L., Tozaki, T., Rubin, C.J., Andersson, L. :
The evolutionary history of the DMRT3 'Gait keeper' haplotype. Anim Genet 48:551-559, 2017. Pubmed reference: 28741731. DOI: 10.1111/age.12580.
2012 Andersson, L.S., Larhammar, M., Memic, F., Wootz, H., Schwochow, D., Rubin, C.J., Patra, K., Arnason, T., Wellbring, L., Hjälm, G., Imsland, F., Petersen, J.L., McCue, M.E., Mickelson, J.R., Cothran, G., Ahituv, N., Roepstorff, L., Mikko, S., Vallstedt, A., Lindgren, G., Andersson, L., Kullander, K. :
Mutations in DMRT3 affect locomotion in horses and spinal circuit function in mice. Nature 488:642-6, 2012. Pubmed reference: 22932389. DOI: 10.1038/nature11399.

Edit History

  • Created by Imke Tammen2 on 04 Jun 2024
  • Changed by Imke Tammen2 on 04 Jun 2024
  • Changed by Imke Tammen2 on 05 Jun 2024