OMIA:000202-10047 : Coat colour, oculocutaneous albinism type I (OCA1), TYR-related in Meriones unguiculatus |
In other species: domestic cat , cattle , dog , rabbit , water buffalo , ass , Japanese medaka , American mink , humpback whale , domestic ferret , pig , domestic guinea pig , Tufted capuchin , dark-spotted frog , Japanese wrinkled frog , Rice frog , lion , red fox , hamadryas baboon , red deer , Japanese raccoon dog , Japanese ratsnake ,
Categories: Pigmentation phene
Possibly relevant human trait(s) and/or gene(s)s (MIM numbers): 203100 (trait) , 606952 (trait) , 606933 (gene)
Links to MONDO diseases: No links.
Mendelian trait/disorder: yes
Mode of inheritance: Autosomal recessive
Considered a defect: no
Key variant known: yes
Year key variant first reported: 2016
Cross-species summary: Congenital lack of pigment in most parts of the body. Due to a non-functional form of the enzyme tyrosinase. Also known as Oculocutaneous albinism (OCA), Acromelanism and as the Himalayan coat-colour pattern
Associated gene:
| Symbol | Description | Species | Chr | Location | OMIA gene details page | Other Links |
|---|---|---|---|---|---|---|
| Tyr | Meriones unguiculatus | - | no genomic information (-..-) | Tyr | Ensembl |
References
Note: the references are listed in reverse chronological order (from the most recent year to the earliest year), and alphabetically by first author within a year.
| 2016 | Ukaji, T., Iwasa, M.A., Kai, O. : |
| Tyrosinase (Tyr) gene mutation in albino Mongolian gerbil (Meriones unguiculatus) Open Journal of Animal Sciences 6(04):259-268, 2016. DOI: 10.4236/ojas.2016.64031. | |
| 1989 | Matsuzaki, T., Yasuda, Y., Nonaka, S. : |
| The Genetics of Coat Colors in the Mongolian Gerbil (Meriones- Unguiculatus) Experimental Animals 38:337-341, 1989. Pubmed reference: 2806391 . |
Edit History
- Created by Frank Nicholas on 06 May 2019