OMIA 000202-10047 : Coat colour, oculocutaneous albinism type I (OCA1), TYR-related in Meriones unguiculatus

In other species: domestic cat , cattle , dog , rabbit , water buffalo , ass , Japanese medaka , American mink , humpback whale , domestic ferret , pig , domestic guinea pig , Tufted capuchin , dark-spotted frog , Japanese wrinkled frog , Rice frog , lion , red fox , hamadryas baboon , red deer , Japanese raccoon dog , Japanese ratsnake

Possibly relevant human trait(s) and/or gene(s)s (MIM numbers): 203100 , 606952 , 606933

Mendelian trait/disorder: yes

Mode of inheritance: Autosomal Recessive

Considered a defect: no

Key variant known: yes

Year key variant first reported: 2016

Cross-species summary: Congenital lack of pigment in most parts of the body. Due to a non-functional form of the enzyme tyrosinase. Also known as Oculocutaneous albinism (OCA), Acromelanism and as the Himalayan coat-colour pattern

Associated gene:

Symbol Description Species Chr Location OMIA gene details page Other Links
Tyr Meriones unguiculatus - no genomic information (-..-) Tyr Ensembl

References


Note: the references are listed in reverse chronological order (from the most recent year to the earliest year), and alphabetically by first author within a year.
2016 Ukaji, T., Iwasa, M.A., Kai, O. :
Tyrosinase (Tyr) gene mutation in albino Mongolian gerbil (Meriones unguiculatus) Open Journal of Animal Sciences 6(04):259-268, 2016. DOI: 10.4236/ojas.2016.64031.
1989 Matsuzaki, T., Yasuda, Y., Nonaka, S. :
The Genetics of Coat Colors in the Mongolian Gerbil (Meriones- Unguiculatus) Experimental Animals 38:337-341, 1989. Pubmed reference: 2806391.

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  • Created by Frank Nicholas on 06 May 2019