OMIA:000202-10047 : Coat colour, oculocutaneous albinism type I (OCA1), TYR-related in Meriones unguiculatus (Mongolian gerbil)

In other species: Japanese medaka , dark-spotted frog , Japanese wrinkled frog , Tufted capuchin , Rhesus monkey , hamadryas baboon , dog , red fox , domestic ferret , domestic cat , lion , humpback whale , ass (donkey) , pig , red deer , American bison , taurine cattle , rabbit , golden hamster , domestic guinea pig , Japanese ratsnake , water buffalo , four-striped grass mouse , ocelot gecko , American mink , Japanese raccoon dog , Rice frog

Categories: Pigmentation phene , Vision / eye phene

Links to possible relevant human trait(s) and/or gene(s) in OMIM: 203100 (trait) , 606952 (trait) , 606933 (gene)

Mendelian trait/disorder: yes

Mode of inheritance: Autosomal recessive

Considered a defect: no

Key variant known: yes

Year key variant first reported: 2016

Cross-species summary: Congenital lack of pigment in most parts of the body. Due to a non-functional form of the enzyme tyrosinase. Also known as Oculocutaneous albinism (OCA), Acromelanism and as the Himalayan coat-colour pattern

Associated gene:

Symbol Description Species Chr Location OMIA gene details page Other Links
Tyr Meriones unguiculatus 14 NC_083361.1 (73438551..73354290) Tyr Homologene, Ensembl , NCBI gene

Cite this entry

Nicholas, F. W., Tammen, I., & Sydney Informatics Hub. (2019). OMIA:000202-10047: Online Mendelian Inheritance in Animals (OMIA) [dataset]. https://omia.org/. https://doi.org/10.25910/2AMR-PV70

References

Note: the references are listed in reverse chronological order (from the most recent year to the earliest year), and alphabetically by first author within a year.

2016 Ukaji, T., Iwasa, M.A., Kai, O. :
Tyrosinase (Tyr) gene mutation in albino Mongolian gerbil (Meriones unguiculatus) Open Journal of Animal Sciences 6(04):259-268, 2016. DOI: 10.4236/ojas.2016.64031.
1989 Matsuzaki, T., Yasuda, Y., Nonaka, S. :
The Genetics of Coat Colors in the Mongolian Gerbil (Meriones- Unguiculatus) Experimental Animals 38:337-341, 1989. Pubmed reference: 2806391.

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  • Created by Frank Nicholas on 06 May 2019