OMIA:000202-143630 : Coat colour, oculocutaneous albinism type I (OCA1), TYR-related in Paroedura picta (ocelot gecko)
In other species: Japanese medaka , dark-spotted frog , Japanese wrinkled frog , Tufted capuchin , Rhesus monkey , hamadryas baboon , dog , red fox , domestic ferret , domestic cat , lion , humpback whale , ass (donkey) , pig , red deer , American bison , taurine cattle , rabbit , golden hamster , Mongolian gerbil , domestic guinea pig , Japanese ratsnake , water buffalo , four-striped grass mouse , American mink , Japanese raccoon dog , Rice frog
Categories: Pigmentation phene
Links to MONDO diseases: No links.
Mendelian trait/disorder: unknown
Considered a defect: unknown
Cross-species summary: Congenital lack of pigment in most parts of the body. Due to a non-functional form of the enzyme tyrosinase. Also known as Oculocutaneous albinism (OCA), Acromelanism and as the Himalayan coat-colour pattern
Species-specific description: This phene includes references to studies involving gene edited or genetically modified organisms (GMO).
Yes - variants have been created artificially, e.g. by genetic engineering or gene editing
Have human generated variants been created, e.g. through genetic engineering and gene editing
Cite this entry
|2023||Abe, T., Kaneko, M., Kiyonari, H. :|
|A reverse genetic approach in geckos with the CRISPR/Cas9 system by oocyte microinjection. Dev Biol 497:S0012-1606(23)00032-5:26-32, 2023. Pubmed reference: 36868446. DOI: 10.1016/j.ydbio.2023.02.005.|
- Created by Imke Tammen2 on 09 Mar 2023
- Changed by Imke Tammen2 on 20 Sep 2023
- Changed by Imke Tammen2 on 10 Dec 2023